{"id":"W2897571764","doi":"10.1080/10428194.2018.1515937","title":"A phase I study of romidepsin, gemcitabine, dexamethasone and cisplatin combination therapy in the treatment of peripheral T-cell and diffuse large B-cell lymphoma; the Canadian cancer trials group LY.15 study†","year":2018,"lang":"en","type":"article","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Sunnybrook Health Science Centre; BC Cancer Agency; Princess Margaret Cancer Centre; Health Sciences Centre; Saint John Regional Hospital; Dalhousie University; University of New Brunswick","funders":"","keywords":"Romidepsin; Gemcitabine; Medicine; Internal medicine; Cisplatin; Lymphoma; Dexamethasone; Peripheral T-cell lymphoma; Cancer; Phases of clinical research; Chemotherapy; Oncology; Gastroenterology; Chemistry; Immunology; T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002030736,0.001945266,0.002303183,0.000554193,0.0006750106,0.000938239,0.001237905,0.001013133,0.003731511],"category_scores_gemma":[0.0007279526,0.0005598035,0.001145329,0.0006600406,0.001296056,0.0005326064,0.0003462082,0.00319695,0.0008107268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003247255,"about_ca_system_score_gemma":0.006687961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02767087,"about_ca_topic_score_gemma":0.09036575,"domain_scores_codex":[0.9995054,0.0002080739,0.00001634987,0.00006896378,0.00006781229,0.0001334852],"domain_scores_gemma":[0.9993657,0.00006037873,0.00007326758,0.00003512864,0.000047137,0.0004183411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7037894,0.08340748,0.006345358,0.00157214,0.002093319,0.0004372626,0.0004791598,0.003460946,0.03417959,0.0007343436,0.02095739,0.1425437],"study_design_scores_gemma":[0.6839763,0.2908455,0.01022908,0.00004439425,0.0006872739,0.0002438979,0.00006621666,0.001038781,0.002186819,0.00020747,0.01043152,0.00004284412],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9664655,0.007092741,0.001024638,0.001616937,0.0003927895,0.01130458,0.004527633,0.0002175742,0.007357682],"genre_scores_gemma":[0.9721341,0.005565697,0.003769424,0.001771602,0.000274024,0.005529014,0.004473454,0.00006134066,0.006421357],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02767087,"threshold_uncertainty_score":0.05501962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03095222513590106,"score_gpt":0.3123608756946855,"score_spread":0.2814086505587844,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}