{"id":"W2897763375","doi":"10.1016/j.jocn.2018.09.012","title":"Efficacy and safety of teriflunomide in Asian patients with relapsing forms of multiple sclerosis: A subgroup analysis of the phase 3 TOWER study","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Neuroscience","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Sanofi","keywords":"Teriflunomide; Medicine; Adverse effect; Multiple sclerosis; Placebo; Internal medicine; Subgroup analysis; Population; Phases of clinical research; Clinical trial; Confidence interval; Alternative medicine; Psychiatry; Pathology; Environmental health; Fingolimod","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002943892,0.0009963827,0.002674774,0.0005185713,0.0003688048,0.0006689461,0.0004372323,0.0005710122,0.001304667],"category_scores_gemma":[0.00161368,0.0002774992,0.004246061,0.0007136579,0.0003014159,0.0004637265,0.000339499,0.000881114,0.0002429024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000352761,"about_ca_system_score_gemma":0.0008145537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001018665,"about_ca_topic_score_gemma":0.0035698,"domain_scores_codex":[0.9992375,0.0003542939,0.0001478022,0.00009512391,0.00007525839,0.00008995139],"domain_scores_gemma":[0.9990498,0.0002280529,0.0002743335,0.0001690542,0.0001186546,0.0001600904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6933118,0.00208033,0.1609596,0.001972288,0.04515693,0.000806107,0.0005017135,0.001188814,0.02926374,0.0001571861,0.001756547,0.06284488],"study_design_scores_gemma":[0.1503606,0.08921283,0.6579741,0.0003060661,0.08207602,0.001991549,0.0009937257,0.00371077,0.006888384,0.0008168631,0.005459418,0.0002098168],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938001,0.00399527,0.0002762225,0.0001420165,0.00005468786,0.000330525,0.0007572261,0.00001959369,0.0006243644],"genre_scores_gemma":[0.9967078,0.001067079,0.0004032639,0.0002596391,0.00009667638,0.0002472372,0.0009390221,0.00001030647,0.0002689338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002943892,"threshold_uncertainty_score":0.01556897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.115889742265125,"score_gpt":0.4142076668412956,"score_spread":0.2983179245761706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}