{"id":"W2897785134","doi":"10.1016/j.scr.2018.10.016","title":"Generation of human induced pluripotent stem cell (iPSC) line from an unaffected female carrier of mutation in SACSIN gene","year":2018,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministerio de Ciencia e Innovación","keywords":"Induced pluripotent stem cell; Reprogramming; Biology; SOX2; KLF4; Mutation; Immunocytochemistry; Cell culture; Spinocerebellar ataxia; Gene; Molecular biology; Genetics; Cell biology; Cancer research; Embryonic stem cell; Endocrinology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001583254,0.0002263294,0.0003491175,0.0004476735,0.0001546494,0.00004039418,0.0005541432,0.0003769838,0.00007162712],"category_scores_gemma":[0.00002426178,0.0002273294,0.00009178329,0.0006347882,0.0002784257,0.00002006065,0.0003333363,0.0003555228,0.00002226506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001119743,"about_ca_system_score_gemma":0.0003632713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001549861,"about_ca_topic_score_gemma":0.001480416,"domain_scores_codex":[0.9957402,0.001225667,0.0006645627,0.000690453,0.001058481,0.0006206631],"domain_scores_gemma":[0.9974768,0.00006682567,0.0002001231,0.0009121756,0.001130753,0.0002133476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002435989,0.0003799601,0.002277288,0.0001181979,0.0000269754,0.00001406,0.0007951542,0.0001279224,0.9922718,0.000004873221,0.0001035443,0.003636607],"study_design_scores_gemma":[0.00137867,0.00262084,0.003076962,0.00003886305,0.00000985809,0.000001400462,0.001104185,0.00199956,0.9894609,0.00001396463,0.00009897212,0.0001958199],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971727,0.0005651799,0.0001892595,0.00002546528,0.00009935131,0.0008622637,0.0001201172,0.000009681695,0.0009559985],"genre_scores_gemma":[0.9972041,0.00008710189,0.0001536286,0.000009567048,0.0003662359,0.0000519866,0.0006763192,0.00005468039,0.001396442],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003440787,"threshold_uncertainty_score":0.9270222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1028725932569353,"score_gpt":0.3693986821260095,"score_spread":0.2665260888690743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}