{"id":"W2897881000","doi":"10.1089/bioe.2018.0003","title":"Selective Serotonin Reuptake Inhibitor Use During Pregnancy and Major Malformations: The Importance of Serotonin for Embryonic Development and the Effect of Serotonin Inhibition on the Occurrence of Malformations","year":2018,"lang":"en","type":"review","venue":"Bioelectricity","topic":"Maternal Mental Health During Pregnancy and Postpartum","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"American Heart Association; March of Dimes Foundation","keywords":"Serotonin; Serotonin transporter; Neurotransmitter; Reuptake inhibitor; Serotonin reuptake inhibitor; Pregnancy; Gestation; Pharmacology; Neuroscience; Biology; Serotonin Plasma Membrane Transport Proteins; Bioinformatics; Internal medicine; Endocrinology; Medicine; Receptor; Central nervous system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002834425,0.0004349728,0.0006743405,0.001279698,0.000215054,0.0005055435,0.0004664455,0.0007421181,0.001788423],"category_scores_gemma":[0.0007436264,0.0001391711,0.0003985505,0.00120316,0.0002790552,0.0006008928,0.0003318542,0.0007932727,0.0004574132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003716644,"about_ca_system_score_gemma":0.0009792924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001575797,"about_ca_topic_score_gemma":0.002930316,"domain_scores_codex":[0.9998462,0.00002722911,0.00003688921,0.00002620986,0.0000499121,0.00001350543],"domain_scores_gemma":[0.9997339,0.0001468775,0.00004850938,0.000005510162,0.00005117708,0.00001415253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007948997,0.00004244635,0.001005767,0.02723872,0.0001658885,0.0005192991,0.0001219977,0.0002108927,0.001227183,0.002076606,0.01495356,0.9523582],"study_design_scores_gemma":[0.00002578375,0.0002034413,0.009342778,0.01580679,0.0006084521,0.01170943,0.0002460271,0.0001657421,0.000996559,0.002322397,0.9585402,0.0000324104],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001792505,0.9989717,0.00004526129,0.0001929419,0.00006992659,0.000001964057,0.00001098281,0.000002477981,0.0005255126],"genre_scores_gemma":[0.001111522,0.9984522,0.00006728107,0.00008020446,0.00006656207,0.000002624434,0.00001409582,4.346545e-7,0.0002050942],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001788423,"threshold_uncertainty_score":0.005982935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0398863960755333,"score_gpt":0.3161917610195412,"score_spread":0.2763053649440079,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}