{"id":"W2897892189","doi":"10.1002/9781119248002.ch5","title":"Cellular versus Biochemical Control over Microbial Products","year":2018,"lang":"en","type":"other","venue":"","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"U.S. Department of Energy","keywords":"Aldehyde dehydrogenase; Escherichia coli; Biochemistry; Fumaric acid; Metabolic engineering; Enzyme; Metabolite; Chemistry; Glycerol; Itaconic acid; Industrial microbiology; Dehydratase; Metabolic pathway; Biology; Fermentation; Organic chemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002532314,0.000588608,0.000287901,0.0002816724,0.0002329328,0.001721461,0.0003860253,0.000404962,0.004718855],"category_scores_gemma":[0.0002282256,0.0001650771,0.0002575787,0.0004263058,0.0005744228,0.0006401596,0.0005979548,0.0006050878,0.003034263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005934581,"about_ca_system_score_gemma":0.0003998897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005855112,"about_ca_topic_score_gemma":0.0007917809,"domain_scores_codex":[0.9996436,0.00003475746,0.00002209306,0.0001043483,0.0001404534,0.00005471981],"domain_scores_gemma":[0.9998692,0.00002721374,0.00003070673,0.00002804842,0.00002898053,0.00001574524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00005216446,0.00003116415,0.0002167489,0.000296867,0.000005262367,0.0001097222,0.00006567701,0.0002355311,0.9614106,0.009060123,0.0005016781,0.02801443],"study_design_scores_gemma":[0.000005446623,0.00009404653,0.0007841716,0.00003464471,0.00001313664,0.0001946243,0.00006333423,0.0004499798,0.9119191,0.001031323,0.08540075,0.000009395469],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.4130921,0.07916442,0.1394746,0.002588587,0.001180683,0.0002860474,0.002739909,0.002472112,0.3590014],"genre_scores_gemma":[0.8261937,0.03846577,0.03615894,0.0007556469,0.0002625437,0.0001868412,0.001430462,0.0004054179,0.09614063],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.004718855,"threshold_uncertainty_score":0.01578617,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004815636748292274,"score_gpt":0.2046373583705251,"score_spread":0.1998217216222328,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}