{"id":"W2898148188","doi":"10.4049/jimmunol.1701582","title":"Distinct Roles for CD4+ Foxp3+ Regulatory T Cells and IL-10–Mediated Immunoregulatory Mechanisms during Experimental Visceral Leishmaniasis Caused by <i>Leishmania donovani</i>","year":2018,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Health and Medical Research Council; Medical Research Council; National Institutes of Health; Department of Science and Technology, Ministry of Science and Technology, India; Griffith University; QIMR Berghofer Medical Research Institute","keywords":"FOXP3; Leishmania donovani; Immunology; Biology; Leishmania; Visceral leishmaniasis; T cell; Interleukin 10; Cytokine; Population; Leishmaniasis; Cell biology; Immune system; Parasite hosting; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003671371,0.0006812247,0.0004024072,0.0005149392,0.0001688061,0.0003651905,0.0002737068,0.000549777,0.001415842],"category_scores_gemma":[0.0002154784,0.0003046731,0.0003684906,0.00009487752,0.0005472969,0.0003313551,0.0002048906,0.001227432,0.000330734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002892913,"about_ca_system_score_gemma":0.0001994302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003438419,"about_ca_topic_score_gemma":0.0004134568,"domain_scores_codex":[0.9996251,0.00006864133,0.00004006876,0.00006761491,0.00005659014,0.0001420096],"domain_scores_gemma":[0.9996493,0.00004338236,0.00008757344,0.0000336911,0.00003179962,0.0001542445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008874519,0.000121149,0.0006803992,0.00004497523,0.000005347512,0.0001220247,0.00002606466,0.00003900333,0.9970134,0.00007558304,0.00002915921,0.000955364],"study_design_scores_gemma":[0.0003733847,0.004127432,0.03960555,0.00003889209,0.00009075804,0.001367993,0.0001785933,0.00161191,0.9512724,0.0001843078,0.00112748,0.00002129686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975855,0.0006438887,0.0006505675,0.00007011456,0.00002335101,0.00003437962,0.0001291332,0.00006774544,0.0007953535],"genre_scores_gemma":[0.9970037,0.0002595558,0.0008908345,0.0001377347,0.00003129492,0.00007519356,0.0002826246,0.00002284188,0.001296215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001415842,"threshold_uncertainty_score":0.004736483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0129677055869458,"score_gpt":0.2637860948241245,"score_spread":0.2508183892371787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}