{"id":"W2898148188","doi":"10.4049/jimmunol.1701582","title":"Distinct Roles for CD4+ Foxp3+ Regulatory T Cells and IL-10–Mediated Immunoregulatory Mechanisms during Experimental Visceral Leishmaniasis Caused by <i>Leishmania donovani</i>","year":2018,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Health and Medical Research Council; Medical Research Council; National Institutes of Health; Department of Science and Technology, Ministry of Science and Technology, India; Griffith University; QIMR Berghofer Medical Research Institute","keywords":"FOXP3; Leishmania donovani; Immunology; Biology; Leishmania; Visceral leishmaniasis; T cell; Interleukin 10; Cytokine; Population; Leishmaniasis; Cell biology; Immune system; Parasite hosting; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001171125,0.0004228891,0.0009398592,0.0002696645,0.0006449749,0.0000529243,0.0005245875,0.0002259173,0.000202879],"category_scores_gemma":[0.0002390303,0.0002965918,0.0002387754,0.0002019915,0.001345028,0.0002662804,0.0002990876,0.0005574158,0.00003211645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003382204,"about_ca_system_score_gemma":0.000163993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004017035,"about_ca_topic_score_gemma":0.0000349016,"domain_scores_codex":[0.9970791,0.0003147884,0.0009486728,0.0003389043,0.000544372,0.0007741539],"domain_scores_gemma":[0.9974173,0.0004406668,0.0006872033,0.0005985719,0.0006741204,0.0001821271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004302192,0.0002665115,0.0002273204,0.00005264151,0.001112115,0.00003405228,0.001148037,4.466185e-7,0.9797108,0.0001129428,0.01247971,0.0005532045],"study_design_scores_gemma":[0.008232322,0.00456377,0.06281853,0.0001683143,0.0003409426,0.0007331434,0.002854673,0.00003505303,0.9104009,0.0002317421,0.009265958,0.000354643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878528,0.009235158,0.0001751007,0.001308252,0.0005012279,0.00065907,0.00007303488,0.00005208214,0.0001433094],"genre_scores_gemma":[0.996891,0.0007624413,0.0004053266,0.0002727314,0.0004392239,0.00003036274,0.00001352512,0.00009358995,0.001091864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06930991,"threshold_uncertainty_score":0.9999486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0129677055869458,"score_gpt":0.2637860948241245,"score_spread":0.2508183892371787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}