{"id":"W2898163638","doi":"10.1210/jc.2018-02093","title":"Letter to the Editor: “A Unique Case of Metastatic, Functional, Hereditary Paraganglioma Associated With an SDHC Germline Mutation”","year":2018,"lang":"en","type":"letter","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Adrenal and Paraganglionic Tumors","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Child Health and Human Development; National Institutes of Health","keywords":"Germline; Paraganglioma; Germline mutation; Genetics; Mutation; Medicine; Biology; Pathology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.003493225,0.0005496427,0.002324764,0.0004018907,0.0002154415,0.00001988118,0.0007260535,0.000561915,0.00045993],"category_scores_gemma":[0.002584127,0.000254137,0.0007059152,0.0005257002,0.001254275,0.0001706482,0.0001273265,0.005411493,0.00005761189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003901069,"about_ca_system_score_gemma":0.0007502974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001076184,"about_ca_topic_score_gemma":0.000109991,"domain_scores_codex":[0.9918951,0.003133316,0.002845183,0.0003953108,0.001049322,0.0006818087],"domain_scores_gemma":[0.98908,0.004803289,0.002917079,0.0009557499,0.001945468,0.0002984255],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002066336,0.0002891556,0.00002271218,0.00002776872,0.002193011,0.159474,0.0002398899,0.00008137271,0.000002958773,0.00003215434,0.8349364,0.0006341817],"study_design_scores_gemma":[0.003941807,0.003094498,0.004324538,0.000197099,0.005659788,0.3445758,0.000157149,0.0000374974,0.0001659459,0.0005479577,0.6370093,0.0002885632],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.3638609,0.001596051,0.0008449919,0.6227068,0.009961124,0.0007206471,0.000160026,0.00003926556,0.0001102606],"genre_scores_gemma":[0.0770212,0.00009633677,0.001253573,0.7198229,0.1996809,0.00002786575,0.0002004007,0.0001449184,0.001751992],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2868397,"threshold_uncertainty_score":0.9999911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05932182814247793,"score_gpt":0.359314029108691,"score_spread":0.2999922009662131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}