{"id":"W2898181620","doi":"10.1097/pr9.0000000000000696","title":"NEO6860, modality-selective TRPV1 antagonist: a randomized, controlled, proof-of-concept trial in patients with osteoarthritis knee pain","year":2018,"lang":"en","type":"article","venue":"PAIN Reports","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"NEOMED Institute","funders":"","keywords":"Medicine; Placebo; Osteoarthritis; Anesthesia; Crossover study; Nausea; Adverse effect; Analgesic; Naproxen; Knee pain; Randomized controlled trial; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.007640651,0.0003266357,0.001493328,0.0002090147,0.0001852757,0.00005790548,0.0001361699,0.0001520393,0.0001086286],"category_scores_gemma":[0.01035802,0.0002205854,0.0003177386,0.0005085556,0.0007805442,0.000192157,0.00005042564,0.0002388184,0.000002553569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007028184,"about_ca_system_score_gemma":0.0002062109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001169923,"about_ca_topic_score_gemma":0.00004063892,"domain_scores_codex":[0.9926206,0.004011065,0.001369292,0.0007622158,0.0007211349,0.0005156225],"domain_scores_gemma":[0.9963824,0.00182844,0.0010705,0.0003250903,0.0002628209,0.0001307249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9484831,0.001219402,0.00279378,0.00004059035,0.00006181904,0.0002768183,0.002749004,0.00009296878,0.0006111326,0.0001000085,0.0005703674,0.04300102],"study_design_scores_gemma":[0.9151433,0.005061678,0.00007214199,0.0001932847,0.00005016743,0.00002686169,0.0001162168,0.001075142,0.07560375,0.001683278,0.0005005877,0.0004736253],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833449,0.00009352473,0.002839193,0.0002332304,0.001826786,0.009509251,0.00001459929,0.00007994509,0.002058597],"genre_scores_gemma":[0.9980334,0.000002974253,0.000109626,0.0003202261,0.0003461614,0.0006631669,0.00001074423,0.00003787104,0.0004758001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07499261,"threshold_uncertainty_score":0.9979782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009257854586045363,"score_gpt":0.2334772890698943,"score_spread":0.224219434483849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}