{"id":"W2898181620","doi":"10.1097/pr9.0000000000000696","title":"NEO6860, modality-selective TRPV1 antagonist: a randomized, controlled, proof-of-concept trial in patients with osteoarthritis knee pain","year":2018,"lang":"en","type":"article","venue":"PAIN Reports","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"NEOMED Institute","funders":"","keywords":"Medicine; Placebo; Osteoarthritis; Anesthesia; Crossover study; Nausea; Adverse effect; Analgesic; Naproxen; Knee pain; Randomized controlled trial; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001641669,0.001215927,0.002474094,0.0003591264,0.0003081729,0.0008857006,0.0009252147,0.00167634,0.005896187],"category_scores_gemma":[0.001238961,0.0005621237,0.001294991,0.0003824499,0.0007479684,0.0009009998,0.000330114,0.001773358,0.000797783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003711921,"about_ca_system_score_gemma":0.001115241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004296793,"about_ca_topic_score_gemma":0.001253443,"domain_scores_codex":[0.9995452,0.0001977976,0.00003854206,0.00008277325,0.00006075251,0.0000749569],"domain_scores_gemma":[0.9994076,0.000150279,0.0001754978,0.00003840336,0.00005821386,0.0001699474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9553668,0.009311615,0.000442986,0.002014854,0.0007606898,0.00006223653,0.00006587131,0.0001941053,0.01020219,0.0001233162,0.0006634567,0.02079182],"study_design_scores_gemma":[0.9333336,0.06466446,0.00096276,0.00003275177,0.0001984399,0.00003011058,0.00001183856,0.0001133914,0.0002730383,0.00004516504,0.0003275374,0.000006984377],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777134,0.009830781,0.00119838,0.0006840889,0.0006195488,0.006754301,0.001203566,0.0001626176,0.001833307],"genre_scores_gemma":[0.9736198,0.00725859,0.00327659,0.001663448,0.0007233054,0.008945332,0.001175024,0.00002814301,0.003309704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005896187,"threshold_uncertainty_score":0.01972467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009257854586045363,"score_gpt":0.2334772890698943,"score_spread":0.224219434483849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}