{"id":"W2898183703","doi":"10.1093/annonc/mdy285.160","title":"Long-term tolerability of olaparib tablets as maintenance therapy for platinum-sensitive relapsed ovarian cancer (PSR OC): Phase III SOLO2 trial","year":2018,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"PARP inhibition in cancer therapy","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"OncoMed Pharmaceutical","keywords":"Olaparib; Medicine; Tolerability; Internal medicine; Adverse effect; Nausea; PARP inhibitor; Placebo; Vomiting; Oncology; Gastroenterology; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001142355,0.0009487849,0.001219185,0.0002200117,0.0002538038,0.001068733,0.0005990395,0.0009403868,0.005685406],"category_scores_gemma":[0.00107738,0.0003387383,0.001326341,0.0003291273,0.0005952124,0.000849622,0.000376227,0.001732396,0.0007769857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007696911,"about_ca_system_score_gemma":0.0006327743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003318834,"about_ca_topic_score_gemma":0.0008345132,"domain_scores_codex":[0.9996414,0.0001622613,0.0000212244,0.00006931871,0.00005005402,0.00005574501],"domain_scores_gemma":[0.999164,0.0001490345,0.0002732204,0.00007460802,0.00003691917,0.0003021806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9002988,0.01367448,0.008142869,0.001194001,0.001639842,0.0002684017,0.000228793,0.0009469534,0.01158869,0.000131698,0.003266819,0.05861869],"study_design_scores_gemma":[0.80065,0.1681587,0.02189325,0.00012774,0.001179108,0.0006437398,0.00008594603,0.001061229,0.002183861,0.000258757,0.003714389,0.00004322874],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993735,0.002431358,0.0001461975,0.0002914236,0.00005763985,0.0006552708,0.001437603,0.00003437624,0.001211018],"genre_scores_gemma":[0.9910787,0.001433117,0.0004683439,0.0006722881,0.000192338,0.001080355,0.003257249,0.00002352415,0.00179406],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005685406,"threshold_uncertainty_score":0.0190196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1234890369426069,"score_gpt":0.46366195840004,"score_spread":0.3401729214574331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}