{"id":"W2898221500","doi":"10.1093/annonc/mdy284.052","title":"The neutrophil-to-lymphocyte ratio (NLR) as a predictive marker of response to abiraterone acetate: A retrospective analysis of the COU302 study","year":2018,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Québec","funders":"","keywords":"Medicine; Abiraterone acetate; Proportional hazards model; Internal medicine; Prednisone; Hazard ratio; Prostate cancer; Progression-free survival; Enzalutamide; Placebo; Survival analysis; Oncology; Neutrophil to lymphocyte ratio; Lymphocyte; Gastroenterology; Cancer; Chemotherapy; Androgen deprivation therapy; Confidence interval; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004300864,0.0003491903,0.0005546274,0.0006294769,0.00023891,0.0007847227,0.000412865,0.0002754831,0.0004595211],"category_scores_gemma":[0.004070797,0.0003230125,0.0006417723,0.001019748,0.000322901,0.0002935942,0.0004751268,0.000486324,0.0001569936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003094315,"about_ca_system_score_gemma":0.0003858912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001136394,"about_ca_topic_score_gemma":0.00147195,"domain_scores_codex":[0.996999,0.001272917,0.0003829932,0.0005520523,0.000656426,0.0001366342],"domain_scores_gemma":[0.993643,0.001587439,0.00269663,0.001079296,0.0006007918,0.0003928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004469304,0.00005304854,0.9901356,0.0000478842,0.0004905924,0.00008302791,0.00006453363,0.0001750947,0.000918337,0.00003671529,0.000198818,0.003327145],"study_design_scores_gemma":[0.0003137256,0.001329056,0.9938053,0.00002133436,0.0006241241,0.0006581307,0.00008860658,0.0008016435,0.0007063234,0.00005272047,0.001579986,0.00001913439],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968024,0.001695952,0.0002893104,0.00002865386,0.000007472681,0.00002838687,0.0007917965,0.000005060823,0.0003509386],"genre_scores_gemma":[0.998601,0.0001940363,0.0001100612,0.0000248597,0.00001237051,0.00001974977,0.0009828166,0.000004210031,0.00005084488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004300864,"threshold_uncertainty_score":0.02274543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05054912373938179,"score_gpt":0.418073508341856,"score_spread":0.3675243846024742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}