{"id":"W2898254906","doi":"10.1007/s11064-018-2657-x","title":"Platelets Bioenergetics Screening Reflects the Impact of Brain Aβ Plaque Accumulation in a Rat Model of Alzheimer","year":2018,"lang":"en","type":"article","venue":"Neurochemical Research","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Agencia Nacional de Promoción Científica y Tecnológica; Canadian Institutes of Health Research; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Bioenergetics; Neurology; Oxidative stress; Biomarker; Platelet; Neurochemistry; Oxidative phosphorylation; Neuroscience; Biology; Internal medicine; Hippocampal formation; Endocrinology; Medicine; Cell biology; Biochemistry; Mitochondrion","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000730446,0.0001493141,0.0003269065,0.0003276474,0.00007577101,0.00001438853,0.0002338808,0.0001307808,0.00006575583],"category_scores_gemma":[0.001559385,0.00009554732,0.0001514039,0.0008442848,0.0006146907,0.00007862702,0.0002030767,0.0005889844,0.0000139591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007210843,"about_ca_system_score_gemma":0.0005336961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000252815,"about_ca_topic_score_gemma":0.00001008031,"domain_scores_codex":[0.9973212,0.0002551849,0.0003540781,0.0003237083,0.001114962,0.0006307991],"domain_scores_gemma":[0.9977912,0.0007192545,0.00006846472,0.0005011788,0.0006100766,0.0003098535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004472099,0.0007639582,0.01119061,0.00005757594,0.001095804,0.00006872406,0.0003235808,0.0003989728,0.9754634,0.000102431,0.00399358,0.002069203],"study_design_scores_gemma":[0.002732467,0.001537106,0.01023694,0.0001773805,0.0000768722,0.00001413525,0.00003441694,0.1237704,0.8601378,0.001162997,0.00001646971,0.0001030816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996839,0.0006217852,0.0000613955,0.001054718,0.000008516638,0.0005488062,0.00001885543,0.00001290409,0.0008340282],"genre_scores_gemma":[0.9992822,0.00009055923,0.0003813304,0.00004793075,0.00008815219,0.00002519057,0.00003466996,0.00002914165,0.00002082216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1233714,"threshold_uncertainty_score":0.3896307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.27583049798972,"score_gpt":0.5039645206050626,"score_spread":0.2281340226153425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}