{"id":"W2898346417","doi":"10.1016/j.jalz.2018.06.1450","title":"P3‐094: A NOVEL TRANSGENIC RAT MODEL OF TAUOPATHY WITH SEVERE BRAIN ATROPHY, GLIOSIS AND COGNITIVE DEFICITS","year":2018,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University","keywords":"Tauopathy; Neuroscience; Tau protein; Gliosis; Atrophy; Psychology; Pathology; Cognitive decline; Microglia; Neurodegeneration; Biology; Dementia; Medicine; Alzheimer's disease; Disease; Internal medicine; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000514632,0.002607248,0.0009521396,0.002121243,0.001042716,0.0005502161,0.001588878,0.001942552,0.003601568],"category_scores_gemma":[0.0002347463,0.0008264943,0.0009679607,0.000670006,0.001445125,0.0008162631,0.000684793,0.002666073,0.001816819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001603912,"about_ca_system_score_gemma":0.001767307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008225744,"about_ca_topic_score_gemma":0.01641267,"domain_scores_codex":[0.9994023,0.00005100281,0.00005607571,0.0001435817,0.0001735339,0.0001734664],"domain_scores_gemma":[0.9992728,0.00004624255,0.0002374025,0.00007671281,0.0001061649,0.0002607789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008310484,0.001236344,0.0004460271,0.00007394145,0.00002586256,0.0008494233,0.0001337666,0.0002685013,0.9925441,0.000609818,0.0006247276,0.002356453],"study_design_scores_gemma":[0.001046627,0.01480565,0.01311113,0.000086987,0.0002139944,0.004824269,0.0003036816,0.005062184,0.9463933,0.001050923,0.01297165,0.0001295775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841945,0.0005468442,0.006082372,0.0006838579,0.0001491924,0.0005073439,0.00359058,0.0008940786,0.003351116],"genre_scores_gemma":[0.9115646,0.00137434,0.02655578,0.000608889,0.0001127637,0.001912252,0.008096975,0.0005338395,0.04924052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008225744,"threshold_uncertainty_score":0.01635569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03290644659675804,"score_gpt":0.2882409873378951,"score_spread":0.255334540741137,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}