{"id":"W2898348027","doi":"10.1093/annonc/mdy424.054","title":"Overall survival at 4 years of follow-up in a phase III trial of nivolumab plus ipilimumab combination therapy in advanced melanoma (CheckMate 067)","year":2018,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Nivolumab; Ipilimumab; Oncology; Melanoma; Internal medicine; Immunotherapy; Cancer; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001873938,0.0007648031,0.001631777,0.0002740936,0.0003794473,0.0009427651,0.0007009141,0.0009004484,0.002242937],"category_scores_gemma":[0.0009446762,0.0003064683,0.002167022,0.0003012272,0.000482512,0.0006712884,0.000412853,0.00250571,0.0004282588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008837286,"about_ca_system_score_gemma":0.0009872571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00143006,"about_ca_topic_score_gemma":0.004110911,"domain_scores_codex":[0.9995845,0.000177068,0.00001900063,0.00009175991,0.00003183998,0.00009593923],"domain_scores_gemma":[0.9994336,0.0001198256,0.000105394,0.00005720514,0.00003276173,0.0002511631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8657733,0.01227151,0.0152117,0.0005949807,0.003731537,0.0001708611,0.0001784351,0.003623609,0.01169461,0.0001672317,0.004483774,0.08209855],"study_design_scores_gemma":[0.4539394,0.4352466,0.09560858,0.0001254163,0.004758427,0.0003548478,0.0001204418,0.002988664,0.002894283,0.0003622018,0.003544408,0.00005662841],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958754,0.001660284,0.0001377153,0.0002350283,0.0001113487,0.0002251597,0.000765763,0.00003050869,0.0009588297],"genre_scores_gemma":[0.9933587,0.001026637,0.0004264802,0.0004613767,0.0001152692,0.0004307414,0.002381201,0.00001443906,0.001785281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002242937,"threshold_uncertainty_score":0.009910464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07025226007946675,"score_gpt":0.3951179964264698,"score_spread":0.324865736347003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}