{"id":"W2898363902","doi":"10.1111/bph.14527","title":"<scp>Nitric oxide</scp> in the gastrointestinal tract: opportunities for drug development","year":2018,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Inflammatory bowel disease; Irritable bowel syndrome; Nitric oxide; Gastrointestinal tract; Pathogenesis; Drug; Medicine; Pharmacology; Rifaximin; Disease; Drug development; Gastroenterology; Ulcerative colitis; Internal medicine; Chemistry; Biochemistry; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003121837,0.0003702725,0.001890207,0.0006154127,0.0001189192,0.00005391643,0.0005256516,0.0001559812,0.00007585617],"category_scores_gemma":[0.0008500135,0.0002912607,0.0006439899,0.0003222185,0.0001540134,0.0001057291,0.00005178744,0.001292136,0.0000230802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000224283,"about_ca_system_score_gemma":0.001930511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001202613,"about_ca_topic_score_gemma":0.000006922112,"domain_scores_codex":[0.9966385,0.0005859915,0.001540871,0.0002495316,0.0003912538,0.0005938323],"domain_scores_gemma":[0.9950671,0.003067554,0.001168481,0.0000918763,0.0003960248,0.0002089725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003574588,0.0005700458,0.00002773549,0.008311197,0.0001889504,0.01457905,0.0001002332,3.285629e-7,0.00002514642,0.000003395047,0.2800534,0.6961048],"study_design_scores_gemma":[0.001996483,0.0003057848,0.0001369861,0.01239819,0.001605382,0.1680596,0.0002707298,0.000001778368,0.00002819374,0.00001549263,0.8150946,0.00008675401],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0101205,0.9870656,0.0001033095,0.000123029,0.0005412772,0.001280256,0.00003369135,0.00001458784,0.000717726],"genre_scores_gemma":[0.0001809004,0.9912806,0.003091066,0.0009751943,0.002188333,0.0001571026,0.00003659842,0.00006942479,0.002020813],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.696018,"threshold_uncertainty_score":0.9999539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1015291729694033,"score_gpt":0.3651714310761235,"score_spread":0.2636422581067203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}