{"id":"W2898380226","doi":"10.1074/jbc.ra118.005485","title":"Structural and kinetic characterization of (S)-1-amino-2-propanol kinase from the aminoacetone utilization microcompartment of Mycobacterium smegmatis","year":2018,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Canadian Light Source","keywords":"Mycobacterium smegmatis; Biochemistry; Enzyme; Kinase; Operon; Biology; Phosphofructokinase 2; Mycobacterium; Streptomyces coelicolor; Dehydratase; Bacteria; Mutant; Genetics; Mycobacterium tuberculosis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001088669,0.0002846835,0.0002143346,0.0001507596,0.0001443062,0.0002545726,0.0003293903,0.0002517618,0.0003857707],"category_scores_gemma":[0.0002612596,0.0001547985,0.0003211602,0.0003179377,0.0001387816,0.0002085647,0.0001319492,0.0003756609,0.0002417529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005176332,"about_ca_system_score_gemma":0.0002551492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004714009,"about_ca_topic_score_gemma":0.003373804,"domain_scores_codex":[0.9999185,0.000007691153,0.000006746323,0.00002072755,0.00003014044,0.00001614616],"domain_scores_gemma":[0.9998542,0.00002644215,0.00004497841,0.00001536397,0.00003053864,0.00002857088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003073612,0.0001023023,0.004500674,0.0001017113,0.00002140924,0.0001467519,0.00008413555,0.002758191,0.9891325,0.0001784344,0.0001222772,0.002544129],"study_design_scores_gemma":[0.00003726218,0.0003942916,0.04424122,0.00001399168,0.00006138616,0.0004206561,0.0001759719,0.03260771,0.9184283,0.0001602328,0.003419592,0.00003936677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982111,0.0003075278,0.0006261329,0.0000573338,0.000005011301,0.000004884642,0.000471096,0.00002097322,0.0002959531],"genre_scores_gemma":[0.9947234,0.0002692513,0.001913448,0.00001534505,0.000003446448,0.00000864926,0.002480581,0.00001937938,0.0005665823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004714009,"threshold_uncertainty_score":0.009373128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01892223043586746,"score_gpt":0.2351555365767871,"score_spread":0.2162333061409197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}