{"id":"W2898448543","doi":"10.1002/cmdc.201800639","title":"Antimicrobial and Antibiofilm Activity of Disubstituted Bis‐benzimidazolium Salts","year":2018,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Lipophilicity; Biofilm; Chemistry; Antimicrobial; Staphylococcus aureus; Bacteria; Transmembrane protein; Phospholipid; Combinatorial chemistry; Microbiology; Biochemistry; Membrane; Organic chemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001025802,0.0003197396,0.0001665001,0.000158112,0.00008057873,0.0001360035,0.0001965099,0.0001754112,0.0004623146],"category_scores_gemma":[0.000196893,0.00009215571,0.0001294216,0.00013478,0.00009278291,0.0001541533,0.0001020511,0.0002542192,0.0001315054],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001960929,"about_ca_system_score_gemma":0.0002085323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00059531,"about_ca_topic_score_gemma":0.00129025,"domain_scores_codex":[0.9998885,0.00002392296,0.0000177126,0.00001220656,0.00003735081,0.00002019501],"domain_scores_gemma":[0.9998922,0.00001598203,0.00003745317,0.00000610909,0.00002755019,0.00002069625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000652417,0.00001569435,0.00009500391,0.00007203926,0.000003520293,0.00002813682,0.00001000091,0.0000979321,0.9983424,0.00005707074,0.00001798616,0.001195018],"study_design_scores_gemma":[0.000008699566,0.0004526793,0.0007833855,0.000006619051,0.00001443288,0.00004265984,0.00000780461,0.0003063078,0.9974203,0.000006270528,0.0009466725,0.000004211824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943547,0.003250628,0.000956754,0.00006193566,0.00003729491,0.00002337792,0.0001115918,0.00002905038,0.001174628],"genre_scores_gemma":[0.9938827,0.002097365,0.002596271,0.00003935147,0.00001034253,0.00002333346,0.0001656746,0.000008182104,0.001176981],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00059531,"threshold_uncertainty_score":0.001546621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01056577687549383,"score_gpt":0.2387487187611811,"score_spread":0.2281829418856872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}