{"id":"W2898448543","doi":"10.1002/cmdc.201800639","title":"Antimicrobial and Antibiofilm Activity of Disubstituted Bis‐benzimidazolium Salts","year":2018,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Lipophilicity; Biofilm; Chemistry; Antimicrobial; Staphylococcus aureus; Bacteria; Transmembrane protein; Phospholipid; Combinatorial chemistry; Microbiology; Biochemistry; Membrane; Organic chemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009247281,0.0001601481,0.0001923545,0.00003088472,0.00007351529,0.00001881104,0.00009851556,0.0001948168,0.000015025],"category_scores_gemma":[0.00004922145,0.0001517469,0.00005857216,0.00009157618,0.0003984682,0.000006654264,0.0001412976,0.00006413684,0.000004710365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005957688,"about_ca_system_score_gemma":0.00005562463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003850712,"about_ca_topic_score_gemma":0.00002452172,"domain_scores_codex":[0.9991792,0.00001816681,0.0001550909,0.0003334156,0.00006627238,0.0002478419],"domain_scores_gemma":[0.9994259,0.00000656895,0.0001031966,0.0002855145,0.00009355522,0.00008528536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001554683,0.00005294827,0.0008524773,0.00003279161,0.00002926995,0.000001289201,0.00002831348,9.53342e-8,0.9955785,0.00003027875,0.001337295,0.001901324],"study_design_scores_gemma":[0.0004704845,0.00009217153,0.004385151,0.00002192847,0.00001451082,0.00002228199,0.00000941161,0.00001194721,0.9907565,0.000002515036,0.004031918,0.0001812072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979582,0.0000825848,0.00004096027,0.0001559661,0.0002797324,0.00009326331,0.00003062501,0.0000150243,0.001343666],"genre_scores_gemma":[0.998364,0.00007315146,0.0007433014,0.0001050717,0.0005336367,6.814701e-7,0.0000538614,0.00001946182,0.0001067798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004821975,"threshold_uncertainty_score":0.6188058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01056577687549383,"score_gpt":0.2387487187611811,"score_spread":0.2281829418856872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}