{"id":"W2898496239","doi":"10.15252/embr.201745536","title":"FMRP recruitment of β‐catenin to the translation pre‐initiation complex represses translation","year":2018,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; York University; Government of Canada","keywords":"Translation (biology); Biology; Cell biology; Catenin; Genetics; Eukaryotic translation; Computational biology; Signal transduction; Messenger RNA; Gene; Wnt signaling pathway","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003627824,0.00009693342,0.00009703277,0.00002606247,0.00007318073,0.00001336971,0.00008604764,0.00006965501,0.0000541011],"category_scores_gemma":[0.0001162361,0.00007992946,0.00007072806,0.0001034202,0.00005574506,0.000004880206,0.00001855184,0.00003051006,0.000003503676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008595835,"about_ca_system_score_gemma":0.00005905226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001949925,"about_ca_topic_score_gemma":0.00003792333,"domain_scores_codex":[0.9989589,0.00007646545,0.0003602405,0.0002954167,0.0001907577,0.0001182133],"domain_scores_gemma":[0.9991492,0.00001755063,0.0001855852,0.0004453962,0.0001519691,0.00005031813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001063023,0.00006436399,0.002559678,0.00001936765,0.00003919227,0.000005648029,0.0006486577,0.0007003743,0.9814356,0.00002371588,0.002262286,0.01213479],"study_design_scores_gemma":[0.0001721316,0.0002420919,0.01782806,0.00002427621,0.00004357938,0.00002870218,0.00002409043,0.0002502063,0.9402058,0.0001965982,0.04086188,0.0001225765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9783881,0.0003310663,0.01621928,0.0004830189,0.0002849228,0.0008437328,0.00002036782,0.00002322821,0.003406272],"genre_scores_gemma":[0.9969493,0.000009373448,0.002128304,0.0001656298,0.0002993715,0.00009027891,0.0002636308,0.00001548143,0.00007858535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04122982,"threshold_uncertainty_score":0.3259429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1164624939020526,"score_gpt":0.3459438932356195,"score_spread":0.2294813993335669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}