{"id":"W2898547808","doi":"10.1155/2018/7089109","title":"Phenotypic Nonspecificity as the Result of Limited Specificity of Transcription Factor Function","year":2018,"lang":"en","type":"review","venue":"Genetics Research International","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Phenotype; Biology; Transcription factor; Genetics; Gene; Pleiotropy; Computational biology; Function (biology)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004349067,0.0006360069,0.0009262957,0.002332819,0.00025269,0.001195645,0.000763763,0.0009784045,0.002737346],"category_scores_gemma":[0.0006867566,0.0002262052,0.0002963168,0.001643176,0.0009668078,0.001405471,0.0007371595,0.00141219,0.001547684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006860776,"about_ca_system_score_gemma":0.0007783808,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007920525,"about_ca_topic_score_gemma":0.001281888,"domain_scores_codex":[0.9998322,0.00002489576,0.00002473087,0.00004585507,0.00005611315,0.00001628881],"domain_scores_gemma":[0.9996684,0.0001662901,0.00005381718,0.00001385027,0.00006342477,0.0000342885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005673151,0.00004399847,0.0004211514,0.01301693,0.00007331151,0.0006337806,0.0001061528,0.0005200965,0.00346436,0.01799911,0.03124261,0.9324217],"study_design_scores_gemma":[0.000005420087,0.00004168329,0.0008453047,0.001817902,0.00005497333,0.003167175,0.00006957064,0.00007387882,0.0007740695,0.004897061,0.9882338,0.00001919842],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001765501,0.9976179,0.000207808,0.0003224873,0.0001296122,0.000002592086,0.00001592556,0.000007640611,0.001519385],"genre_scores_gemma":[0.001427019,0.9973385,0.0001614378,0.0001859051,0.0001345625,0.000004926221,0.00002772997,0.00000204324,0.0007179203],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002737346,"threshold_uncertainty_score":0.0091573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1182565898955458,"score_gpt":0.3849702595444803,"score_spread":0.2667136696489346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}