{"id":"W2898601882","doi":"10.1093/ofid/ofy210.1606","title":"1950. Prevention of Recurrent <i>Clostridium difficile</i> at Six Months Following Treatment With Microbiota-Based Therapy RBX2660: Durability Results From a Phase 2 Open-Label Study","year":2018,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Clinical endpoint; Clostridium difficile; Internal medicine; Phases of clinical research; Open label; Clinical trial; Antibiotics; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009977216,0.0003511404,0.0008548879,0.0001885663,0.0002588158,0.0004956798,0.0003180981,0.0006430115,0.002081376],"category_scores_gemma":[0.0006349301,0.0001663611,0.0007460336,0.0001385023,0.000350656,0.0003658386,0.0001325789,0.0009913273,0.00053398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003259466,"about_ca_system_score_gemma":0.0005485783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001064624,"about_ca_topic_score_gemma":0.002053909,"domain_scores_codex":[0.9996576,0.0001228842,0.00002842106,0.00006237872,0.0000603178,0.00006840817],"domain_scores_gemma":[0.9994965,0.00007911644,0.0001700168,0.00005437557,0.00007431182,0.0001256512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4367222,0.07202732,0.01223674,0.001765825,0.00131655,0.0001982563,0.0002976807,0.0009439312,0.16527,0.0002440223,0.003715743,0.3052618],"study_design_scores_gemma":[0.06929399,0.8624984,0.0440903,0.0001119682,0.0006735813,0.000240234,0.0000780026,0.0006638984,0.01867417,0.00009160482,0.003552635,0.00003118071],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939423,0.002710052,0.0005229639,0.0001612878,0.0000780422,0.0005874734,0.0005573796,0.0000665174,0.001373817],"genre_scores_gemma":[0.9943278,0.001472011,0.0009860677,0.0003902935,0.0001001492,0.0002551803,0.0008673196,0.00001439517,0.001586649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002081376,"threshold_uncertainty_score":0.006962836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05260288721741938,"score_gpt":0.373565557234625,"score_spread":0.3209626700172057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}