{"id":"W2898845456","doi":"10.3747/co.25.4235","title":"Immune-Related Adverse Events of Immune Checkpoint Inhibitors: A Brief Review","year":2018,"lang":"en","type":"review","venue":"Current Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"Horizon Health Network; Moncton Hospital","funders":"","keywords":"Medicine; Discontinuation; Adverse effect; Immunosuppression; Intensive care medicine; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006934346,0.0009969785,0.001351154,0.002340371,0.0003456191,0.0009348294,0.0008314181,0.0009908392,0.004534724],"category_scores_gemma":[0.001718242,0.0002561407,0.001070688,0.002129025,0.0003033439,0.001098364,0.0005564826,0.001161103,0.0008373098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005098527,"about_ca_system_score_gemma":0.001521695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001058273,"about_ca_topic_score_gemma":0.001949563,"domain_scores_codex":[0.9995683,0.00008066837,0.0001290536,0.00006785084,0.0001268313,0.0000273475],"domain_scores_gemma":[0.9988243,0.0006674089,0.0002544474,0.00001730592,0.0001974833,0.00003899897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001100059,0.00007659377,0.0004660639,0.05784812,0.0002217477,0.0002704808,0.00007237188,0.0003504964,0.0005893455,0.001307549,0.0321912,0.906496],"study_design_scores_gemma":[0.00005846862,0.0002480677,0.003361256,0.03531108,0.0009159565,0.00558919,0.00011367,0.0002182629,0.000598894,0.001906335,0.9516271,0.00005161826],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008799117,0.9991221,0.00005154283,0.0001680345,0.0001458546,0.000006196921,0.00002008124,0.000003371959,0.0003948131],"genre_scores_gemma":[0.0007308185,0.9984674,0.0001038658,0.0001713448,0.0002359139,0.000009415413,0.00003492174,8.909452e-7,0.000245377],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004534724,"threshold_uncertainty_score":0.01517016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09874859782321654,"score_gpt":0.4308019298198758,"score_spread":0.3320533319966592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}