{"id":"W2898880167","doi":"10.1016/j.clcc.2018.10.006","title":"5-Fluorouracil-related Cardiotoxicity; Findings From Five Randomized Studies of 5-Fluorouracil-based Regimens in Metastatic Colorectal Cancer","year":2018,"lang":"en","type":"article","venue":"Clinical Colorectal Cancer","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Bevacizumab; Colorectal cancer; Internal medicine; Logistic regression; Cardiotoxicity; Fluorouracil; Oncology; Univariate analysis; Multivariate analysis; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01068933,0.0007756382,0.001509361,0.0007580616,0.0004689879,0.00109126,0.000566147,0.001169465,0.001802655],"category_scores_gemma":[0.0163343,0.000458475,0.003892947,0.001083802,0.001102956,0.0007322664,0.00060516,0.001023594,0.0001170719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001208614,"about_ca_system_score_gemma":0.001146007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001903756,"about_ca_topic_score_gemma":0.005511853,"domain_scores_codex":[0.9896232,0.007397525,0.00142939,0.0006362941,0.0005526695,0.000360801],"domain_scores_gemma":[0.9872079,0.006746292,0.004345685,0.0006434058,0.0005276594,0.00052888],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.7660256,0.003872267,0.08465184,0.008923387,0.07965109,0.0002023053,0.0003165773,0.0008599384,0.006386436,0.0002896831,0.0005152852,0.04830556],"study_design_scores_gemma":[0.4224523,0.1460675,0.233619,0.002220508,0.1845892,0.00059667,0.0005438605,0.0006868632,0.004245213,0.0003997285,0.004458421,0.0001207273],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9431106,0.05349692,0.0004743603,0.0002961676,0.0001243048,0.000752104,0.0004844283,0.00001449683,0.001246466],"genre_scores_gemma":[0.9951637,0.004052296,0.0002172928,0.0001377284,0.00007305504,0.0001066901,0.0001561228,0.00000273723,0.0000902729],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01068933,"threshold_uncertainty_score":0.05653125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06564236374605982,"score_gpt":0.4145528139470809,"score_spread":0.3489104502010211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}