{"id":"W2898934370","doi":"10.1007/s40268-018-0253-9","title":"Efficacy and Safety of Budesonide in the Treatment of Eosinophilic Esophagitis: Updated Systematic Review and Meta-Analysis of Randomized and Non-Randomized Studies","year":2018,"lang":"en","type":"review","venue":"Drugs in R&D","topic":"Eosinophilic Esophagitis","field":"Medicine","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute","keywords":"Randomized controlled trial; Medicine; Budesonide; Internal medicine; Meta-analysis; Eosinophilic esophagitis; Cochrane Library; Placebo; Confidence interval; Relative risk; Adverse effect; Gastroenterology; Asthma; Pathology; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02522507,0.003028569,0.02437038,0.00980965,0.000649792,0.003742461,0.002671797,0.002781447,0.003547362],"category_scores_gemma":[0.05295248,0.00193408,0.0419418,0.008389032,0.0008404704,0.002416306,0.001809063,0.00221438,0.000291623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003501202,"about_ca_system_score_gemma":0.006148806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006482229,"about_ca_topic_score_gemma":0.01251057,"domain_scores_codex":[0.9798185,0.008211139,0.007363882,0.001464039,0.002675783,0.0004667444],"domain_scores_gemma":[0.9721056,0.01724064,0.006203236,0.0008527054,0.003263068,0.0003347547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001539419,0.00003474091,0.002490537,0.4947985,0.4854455,0.0001182934,0.00007916559,0.0003561095,0.000202503,0.0001212325,0.0005793248,0.01423467],"study_design_scores_gemma":[0.0005907189,0.0001745715,0.002088029,0.03450728,0.9608275,0.00008764332,0.00003274636,0.0001091801,0.0001048434,0.0001267032,0.001329265,0.00002154112],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002456499,0.9958072,0.0004243378,0.0002118491,0.0001657389,0.000343545,0.0004002581,0.00001887177,0.0001716992],"genre_scores_gemma":[0.08424626,0.9090614,0.002790264,0.001086005,0.0003096831,0.001334071,0.0009100704,0.00002960945,0.0002326691],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02522507,"threshold_uncertainty_score":0.1334044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06042388775615146,"score_gpt":0.3792141270448372,"score_spread":0.3187902392886857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}