{"id":"W2899084700","doi":"10.1016/s2468-1253(18)30341-8","title":"Efficacy and safety of glecaprevir/pibrentasvir in patients with chronic hepatitis C virus genotype 5 or 6 infection (ENDURANCE-5,6): an open-label, multicentre, phase 3b trial","year":2018,"lang":"en","type":"article","venue":"The Lancet. Gastroenterology & hepatology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Toronto General Hospital; University of Calgary","funders":"","keywords":"Internal medicine; Medicine; Regimen; Hepatitis C virus; Population; Cirrhosis; Clinical endpoint; Gastroenterology; Hepatitis C; Genotype; Clinical trial; Immunology; Virus; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001984344,0.001304578,0.001574788,0.000317124,0.0002471636,0.0008971483,0.0007302872,0.001307685,0.004513429],"category_scores_gemma":[0.001218876,0.0003591808,0.002031779,0.0003279465,0.0008633318,0.001190657,0.0003061821,0.003065045,0.0009860769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007272155,"about_ca_system_score_gemma":0.0006818697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007111788,"about_ca_topic_score_gemma":0.001808759,"domain_scores_codex":[0.9993805,0.0003250718,0.00003410593,0.00008567046,0.00006234602,0.0001123435],"domain_scores_gemma":[0.9993838,0.0001578649,0.0001539727,0.0000498572,0.00003831349,0.0002161147],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9157708,0.005957593,0.00260688,0.001172728,0.002757552,0.00008269953,0.00009977923,0.0008459182,0.005814263,0.0002284026,0.001999661,0.06266358],"study_design_scores_gemma":[0.8865803,0.09857592,0.009972406,0.00009944095,0.001046295,0.0001686011,0.00006782985,0.0007474801,0.0009924313,0.0002867834,0.001421322,0.00004111197],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855613,0.009272562,0.0003043604,0.0007129696,0.0002521266,0.0006783663,0.0008901901,0.00008733445,0.002240792],"genre_scores_gemma":[0.9916033,0.00285178,0.0007626824,0.0009727851,0.0001654786,0.000508189,0.001459887,0.00001703868,0.001658781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004513429,"threshold_uncertainty_score":0.01509899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04659350452469745,"score_gpt":0.3595606740034717,"score_spread":0.3129671694787742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}