{"id":"W2899256508","doi":"10.1534/genetics.118.301456","title":"Transgenerational Epigenetic Inheritance Is Negatively Regulated by the HERI-1 Chromodomain Protein","year":2018,"lang":"en","type":"article","venue":"Genetics","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"RNA interference; Biology; Chromodomain; Genetics; Epigenetics; Gene silencing; RNA silencing; Gene; Genetic screen; Cell biology; RNA; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110809,0.00029711,0.0001508304,0.0002381956,0.0001570367,0.0003002535,0.0002923763,0.0002315475,0.001816546],"category_scores_gemma":[0.0001121334,0.0001676291,0.0001963949,0.00008327149,0.0002470665,0.0001355941,0.0003444834,0.0005826292,0.000789592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00046252,"about_ca_system_score_gemma":0.0001460916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005895124,"about_ca_topic_score_gemma":0.001207355,"domain_scores_codex":[0.9998524,0.00001002997,0.00000978861,0.00004369147,0.00005425371,0.00002982951],"domain_scores_gemma":[0.9997095,0.0000432099,0.0001305555,0.00002193966,0.00002533342,0.00006937548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001264026,0.000005976219,0.0001192964,0.000005181149,8.476396e-7,0.00003020914,0.000002268293,0.00001116768,0.9995252,0.0000398188,0.00001825666,0.0002292529],"study_design_scores_gemma":[0.00001310644,0.00007081764,0.01798533,0.000006617403,0.000008285057,0.0003753511,0.00001996673,0.001831219,0.9774001,0.00006726456,0.002215524,0.000006427228],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914349,0.001159996,0.003768143,0.0001362153,0.00003846419,0.0000163174,0.0005766196,0.0001890167,0.002680423],"genre_scores_gemma":[0.9926494,0.0002380563,0.0009319595,0.00007039279,0.000006725609,0.00001303542,0.0005885768,0.00005355564,0.005448289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001816546,"threshold_uncertainty_score":0.006076932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009120461304376815,"score_gpt":0.2721878289833146,"score_spread":0.2630673676789378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}