{"id":"W2899336126","doi":"10.1186/s13059-018-1564-4","title":"Phytophthora methylomes are modulated by 6mA methyltransferases and associated with adaptive genome regions","year":2018,"lang":"en","type":"article","venue":"Genome biology","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Agriculture and Agri-Food Canada; Recruitment Program of Global Experts; Nanjing Agricultural University; Zhejiang University; Chinese Academy of Sciences; Sun Yat-sen University; Ohio State University","keywords":"Biology; Transposable element; DNA methylation; Genome; Genetics; Epigenetics; Methyltransferase; Gene; Methylated DNA immunoprecipitation; Phytophthora infestans; Methylation; Genome evolution; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005055203,0.0002338083,0.0001516453,0.0002542575,0.0001715326,0.0002409349,0.0001236449,0.0002429997,0.001267655],"category_scores_gemma":[0.0001146326,0.0001658816,0.0002232317,0.0001866704,0.0001643336,0.0001907028,0.0002995115,0.0003673531,0.0003703974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001752429,"about_ca_system_score_gemma":0.000112524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005291861,"about_ca_topic_score_gemma":0.000981205,"domain_scores_codex":[0.9999145,0.00000414063,0.000005049612,0.0000381402,0.000022546,0.00001562144],"domain_scores_gemma":[0.9998105,0.00002088418,0.00009210087,0.00001852863,0.00002146688,0.00003655855],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004954136,0.000003827206,0.001500301,0.00002277537,0.000004163674,0.00001954027,0.00001360457,0.00001777927,0.99763,0.00002502563,0.00002552686,0.0006878478],"study_design_scores_gemma":[0.00001800191,0.0001584181,0.2919434,0.00001561899,0.00005309332,0.0006225425,0.000106325,0.001923736,0.7015021,0.0002857158,0.003356625,0.00001440921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99555,0.0005586582,0.001997209,0.000052675,0.000008979914,0.000008126925,0.001058557,0.0001489093,0.0006169154],"genre_scores_gemma":[0.9950809,0.000253702,0.001495305,0.00004493778,0.00000560957,0.00001430489,0.001745781,0.00003527348,0.001324033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001267655,"threshold_uncertainty_score":0.004240692,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01275089521567797,"score_gpt":0.2411613881554407,"score_spread":0.2284104929397628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}