{"id":"W2899435144","doi":"10.1002/jcb.28044","title":"D224V and S128Y mutation in FSHR<sub>ED</sub> influence thumb movement differentially: An intricate insight gained by short‐term molecular dynamics simulation","year":2018,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Ovarian function and disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Follicle-stimulating hormone receptor; Biology; Receptor; Follicle-stimulating hormone; Mutation; Hormone; Internal medicine; Endocrinology; Cell biology; Genetics; Luteinizing hormone; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000210448,0.0001698559,0.000241199,0.0001355581,0.0000468699,0.00004695495,0.00008642671,0.0001724702,0.00003306187],"category_scores_gemma":[0.000121081,0.0001567329,0.00006776016,0.0001759433,0.00009861234,0.0001377574,0.0000304426,0.0002481489,0.000002323239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001759234,"about_ca_system_score_gemma":0.0001284746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004175977,"about_ca_topic_score_gemma":0.000002403742,"domain_scores_codex":[0.9987263,0.00004418535,0.0005065117,0.0002098449,0.00034251,0.0001706107],"domain_scores_gemma":[0.9990531,0.00002248066,0.0002549998,0.0001976503,0.0002727966,0.0001989508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003702404,0.0002628696,0.005381907,0.00006880426,0.00005283292,0.00007972409,0.0002065248,0.0003335222,0.989373,0.00001293715,0.00003180757,0.003825807],"study_design_scores_gemma":[0.002191304,0.0005339528,0.007335921,0.0001075808,0.00010932,0.00003709271,0.0001683598,0.02426342,0.9648352,0.0002176884,0.00002209997,0.0001781005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9728094,0.0003418553,0.02622311,0.0001939708,0.00007970533,0.0001344877,0.000004231632,0.00001270603,0.0002005258],"genre_scores_gemma":[0.9991617,0.00005073213,0.0001580903,0.0003652587,0.0001131348,0.000001948443,0.00009324616,0.00002033551,0.00003560459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02635224,"threshold_uncertainty_score":0.6391384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004762322564022222,"score_gpt":0.2365199544700979,"score_spread":0.2317576319060756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}