{"id":"W2899550130","doi":"","title":"Transformation of normal NIH-3T3 cells into highly oncogenic and invasive cancer cells by MBD2 overexpression","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"DNA methylation; Biology; Carcinogenesis; Cancer research; Cell culture; Cancer cell; Gene knockdown; Malignant transformation; Molecular biology; 3T3 cells; Cell biology; Cancer; Transfection; Gene expression; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001554453,0.0007835821,0.0003498946,0.0003970454,0.0002627228,0.0003697042,0.0003932716,0.0003445405,0.00194429],"category_scores_gemma":[0.0001163102,0.0002417428,0.0004858532,0.000557899,0.0002787109,0.000149785,0.0003578096,0.0008760113,0.0009355347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00067156,"about_ca_system_score_gemma":0.0003141347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002962919,"about_ca_topic_score_gemma":0.003975384,"domain_scores_codex":[0.999718,0.00002394011,0.00004191067,0.000057146,0.0001042922,0.00005460455],"domain_scores_gemma":[0.9998853,0.00001858889,0.00002862056,0.00002541648,0.00001480784,0.00002724191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004015011,0.00001666937,0.00008659754,0.00001702725,0.000005123334,0.0000452651,0.0000141683,0.00003057557,0.9993235,0.00009018237,0.00004532207,0.000285471],"study_design_scores_gemma":[0.00002386796,0.0001396322,0.002717705,0.000005544734,0.00002334202,0.0003133594,0.00002611018,0.001129891,0.9897336,0.00003894556,0.005841686,0.0000063474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9776643,0.001489288,0.009940649,0.0002341138,0.0001268168,0.0001280051,0.005375745,0.0004709825,0.004570079],"genre_scores_gemma":[0.9737665,0.0007813043,0.006898225,0.00009419831,0.00001726898,0.0001770667,0.00919324,0.0001183724,0.008953842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002962919,"threshold_uncertainty_score":0.006504357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02386025093706391,"score_gpt":0.3583976078385001,"score_spread":0.3345373569014362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}