{"id":"W2899592375","doi":"10.1016/j.pestbp.2018.11.003","title":"Jaburetox, a natural insecticide derived from Jack Bean Urease, activates voltage-gated sodium channels to modulate insect behavior","year":2018,"lang":"en","type":"article","venue":"Pesticide Biochemistry and Physiology","topic":"Insect and Pesticide Research","field":"Agricultural and Biological Sciences","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"University of Toronto; University of Toronto Mississauga; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Cockroach; Xenopus; Electrophysiology; Sodium channel; Voltage clamp; Biology; Compound muscle action potential; Sodium; Insect; Chemistry; Anatomy; Internal medicine; Endocrinology; Pharmacology; Biochemistry; Botany; Medicine; Neuroscience; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006240423,0.0001898236,0.0001366659,0.00007520301,0.00008419965,0.0001201199,0.00009217601,0.0001663994,0.0004927067],"category_scores_gemma":[0.00005153772,0.00006574673,0.0001474103,0.00004175297,0.0001190561,0.0001441527,0.0001117673,0.0002364663,0.0000766697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001123563,"about_ca_system_score_gemma":0.00006861275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004067677,"about_ca_topic_score_gemma":0.00129249,"domain_scores_codex":[0.9999706,0.000003299089,0.000001986243,0.000007279703,0.000007420572,0.000009452981],"domain_scores_gemma":[0.9999785,0.000003025467,0.00000722074,0.000001073353,0.000002844856,0.000007280955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003710859,0.000005630718,0.000127269,0.00001388885,0.000001179145,0.00001212771,0.000004322824,0.000009232717,0.9994023,0.00001025757,0.000003291242,0.0003734941],"study_design_scores_gemma":[0.00003078953,0.001097204,0.02381444,0.00001025483,0.00002215708,0.0002578662,0.00004457884,0.001023759,0.9724556,0.00003180582,0.001206998,0.000004483369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971492,0.001016763,0.001151541,0.00003666103,0.000009539489,0.00001370056,0.0000572228,0.00002409853,0.0005413314],"genre_scores_gemma":[0.9971259,0.000695471,0.001087713,0.00004228084,0.000003761889,0.00001844033,0.00008362533,0.000004174147,0.0009386136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004927067,"threshold_uncertainty_score":0.001648247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02431538243976206,"score_gpt":0.2607670268591555,"score_spread":0.2364516444193935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}