{"id":"W2899675538","doi":"10.1016/j.jsb.2018.11.003","title":"Structural and biochemical characterization of citrate binding to AtPPC3, a plant-type phosphoenolpyruvate carboxylase from Arabidopsis thaliana","year":2018,"lang":"en","type":"article","venue":"Journal of Structural Biology","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Phosphoenolpyruvate carboxylase; Citrate synthase; Allosteric regulation; Biochemistry; ATP citrate lyase; Phosphoenolpyruvate carboxykinase; Pyruvate carboxylase; Binding site; Enzyme; Myrosinase; Arabidopsis thaliana; Chemistry; Cytosol; Biology; Biophysics; Glucosinolate; Mutant; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328028,0.0003158308,0.0002190551,0.0001562682,0.0003718035,0.0002946258,0.0003687388,0.0003117854,0.001206354],"category_scores_gemma":[0.0002898879,0.0001822908,0.0003526016,0.000316297,0.0001999532,0.0002210715,0.000113198,0.0005303166,0.0003867788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009230684,"about_ca_system_score_gemma":0.0005017555,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01323924,"about_ca_topic_score_gemma":0.01134019,"domain_scores_codex":[0.9999337,0.000007816802,0.000004814194,0.00001713382,0.00002323088,0.00001328907],"domain_scores_gemma":[0.999861,0.00002751341,0.00002654005,0.00001193878,0.00003261489,0.00004029468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002416042,0.00005180284,0.00084544,0.00004502563,0.0000103088,0.0001901901,0.00004618676,0.0004178426,0.9966271,0.0002091145,0.000159384,0.001155959],"study_design_scores_gemma":[0.00004669921,0.0001710657,0.04390725,0.0000125543,0.00005523952,0.001249649,0.000252664,0.007914467,0.9385134,0.0002393514,0.007607205,0.00003051419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953489,0.000677229,0.001880434,0.000194441,0.00002474714,0.00001629409,0.0006947554,0.0000455929,0.00111757],"genre_scores_gemma":[0.9928908,0.0003092956,0.002075711,0.0001100142,0.000008151324,0.000009366427,0.002704592,0.00002477272,0.001867256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01323924,"threshold_uncertainty_score":0.02632433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.010447941990194,"score_gpt":0.2463050306539156,"score_spread":0.2358570886637216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}