{"id":"W2899685235","doi":"10.1093/neuonc/noy148.358","title":"EXTH-09. DIANHYDROGALACTITOL (VAL-083) HAS THE POTENTIAL TO OVERCOME MAJOR CHALLENGES IN THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)","year":2018,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Delmar (Canada)","funders":"","keywords":"In vivo; Cancer research; Combination therapy; Medicine; Radiation therapy; Pharmacology; IC50; Cell culture; Biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006992076,0.0002607621,0.0001695893,0.0001416763,0.00007736203,0.0002039251,0.0001913959,0.0001785612,0.001277044],"category_scores_gemma":[0.00004433862,0.00007606177,0.0001646511,0.0001641731,0.0001354118,0.0001175691,0.0001988262,0.0005761865,0.0004541657],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002753361,"about_ca_system_score_gemma":0.0002140197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006471206,"about_ca_topic_score_gemma":0.001605144,"domain_scores_codex":[0.9999582,0.000007189837,0.00000229228,0.000007274824,0.00001520101,0.000009903408],"domain_scores_gemma":[0.9999706,0.00000323435,0.000008808677,0.000003117375,0.000002868631,0.00001135245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004291939,0.0001733447,0.0008029471,0.0002486935,0.00003368648,0.0002433819,0.00003094888,0.0005981579,0.9457886,0.0005316883,0.0007975834,0.05032175],"study_design_scores_gemma":[0.0001880873,0.00416611,0.009261154,0.00002147833,0.00007161355,0.002878016,0.00004961657,0.0009762039,0.928795,0.0002832147,0.05329394,0.00001549613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9693022,0.01783602,0.003700888,0.0005136393,0.00008137237,0.00008889574,0.000826905,0.0002590763,0.007391075],"genre_scores_gemma":[0.9886758,0.004362177,0.002599886,0.0001333118,0.0000142345,0.00003173651,0.001096279,0.00002397616,0.003062504],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001277044,"threshold_uncertainty_score":0.004272103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04265341174979834,"score_gpt":0.3047942839018642,"score_spread":0.2621408721520658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}