{"id":"W2899783743","doi":"10.1016/j.vaccine.2018.10.057","title":"Accelerated onset of chronic wasting disease in elk (Cervus canadensis) vaccinated with a PrPSc-specific vaccine and housed in a prion contaminated environment","year":2018,"lang":"en","type":"article","venue":"Vaccine","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Pan-Provincial Vaccine Enterprise; University of British Columbia Hospital; University of Saskatchewan","funders":"","keywords":"Chronic wasting disease; Vaccination; Genotype; Virology; Biology; Titer; Antibody; Immunology; Medicine; Disease; Prion protein; Internal medicine; Scrapie; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001746575,0.0006028334,0.0004915534,0.0006883817,0.0003680633,0.000527832,0.0003138602,0.0005486034,0.001823044],"category_scores_gemma":[0.0003626404,0.0002736705,0.0003634653,0.0001677856,0.0005797421,0.0005521849,0.0003374084,0.001282951,0.0004043778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006887866,"about_ca_system_score_gemma":0.0004083433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003925133,"about_ca_topic_score_gemma":0.004763584,"domain_scores_codex":[0.9997092,0.00002628095,0.0000151264,0.0001101342,0.00002905227,0.0001101992],"domain_scores_gemma":[0.9995667,0.00005711393,0.00009635426,0.00004084895,0.00004960162,0.0001893768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005288146,0.001158008,0.006129038,0.00005145966,0.00003660751,0.0003718589,0.0002035531,0.00007188316,0.9853433,0.00006496914,0.0001284895,0.001152598],"study_design_scores_gemma":[0.0004035656,0.02198578,0.3754597,0.00005415694,0.000241504,0.002699183,0.001311513,0.002423862,0.5928909,0.0003453174,0.002084427,0.000100081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993404,0.0001239701,0.00007330312,0.00001807973,0.00002310246,0.00001033136,0.0001583456,0.0000118582,0.0002406707],"genre_scores_gemma":[0.996361,0.0001474807,0.0002080071,0.0000644385,0.000008703256,0.00003121756,0.00039411,0.00001500972,0.002770189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003925133,"threshold_uncertainty_score":0.007804573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008571365027656557,"score_gpt":0.2179045971735213,"score_spread":0.2093332321458648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}