{"id":"W2899913309","doi":"10.1002/btpr.2742","title":"Process development for an inducible rituximab‐expressing Chinese hamster ovary cell line","year":2018,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Polytechnique Montréal","funders":"Luonnontieteiden ja Tekniikan Tutkimuksen Toimikunta; National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Canada First Research Excellence Fund","keywords":"Chinese hamster ovary cell; Ovary; Rituximab; Cell culture; Line (geometry); Biology; Cell biology; Chemistry; Genetics; Antibody; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001500663,0.0002754983,0.0002101015,0.0001188423,0.0003904436,0.00005221762,0.0004138761,0.0006560616,0.00002048176],"category_scores_gemma":[0.00004782071,0.0002315744,0.00007593905,0.0001756023,0.0004042814,0.00001625101,0.0002281152,0.0001326839,0.00001949825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000144614,"about_ca_system_score_gemma":0.0001436916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003418658,"about_ca_topic_score_gemma":0.00001820986,"domain_scores_codex":[0.9984037,0.00003281964,0.0002823993,0.0007120491,0.0001156395,0.0004533877],"domain_scores_gemma":[0.9989301,0.000005203876,0.0001505789,0.0005860562,0.0002094078,0.0001186541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005189906,0.001315062,0.00784295,0.0001785085,0.00007770892,0.000004371712,0.000184597,0.000008027404,0.9558108,0.00003833318,0.003221186,0.0307994],"study_design_scores_gemma":[0.001293227,0.001473656,0.0004971112,0.00003686972,0.00001451896,0.00001688089,0.00005251875,0.0001373122,0.9589292,0.0002816722,0.03691596,0.0003510351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934921,0.001354508,0.003508778,0.000202469,0.0004208793,0.0005546238,0.00002164346,0.0001688092,0.0002761864],"genre_scores_gemma":[0.9898074,0.00002195579,0.008366396,0.0003060336,0.0006857507,0.0003598979,0.0001666868,0.00005022168,0.0002356777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03369477,"threshold_uncertainty_score":0.9443331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01743989689279509,"score_gpt":0.3157452692508312,"score_spread":0.2983053723580361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}