{"id":"W2899913309","doi":"10.1002/btpr.2742","title":"Process development for an inducible rituximab‐expressing Chinese hamster ovary cell line","year":2018,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Polytechnique Montréal","funders":"Luonnontieteiden ja Tekniikan Tutkimuksen Toimikunta; National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Canada First Research Excellence Fund","keywords":"Chinese hamster ovary cell; Ovary; Rituximab; Cell culture; Line (geometry); Biology; Cell biology; Chemistry; Genetics; Antibody; Mathematics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000586518,0.0004739589,0.0006139173,0.0003325554,0.0002156361,0.0006511643,0.0005284054,0.0004821773,0.0008155618],"category_scores_gemma":[0.0002648063,0.0002962244,0.0006001765,0.0004871705,0.0001810233,0.0002851444,0.0004700994,0.0009765443,0.001403384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004478223,"about_ca_system_score_gemma":0.0004193725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008416004,"about_ca_topic_score_gemma":0.001265835,"domain_scores_codex":[0.9996514,0.00004810387,0.0000462824,0.00006825616,0.000139857,0.00004610829],"domain_scores_gemma":[0.9998801,0.00001918984,0.0000234918,0.00002398783,0.00003898982,0.00001428158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001484495,0.00002286302,0.00006010709,0.00004049157,0.00000331994,0.00004869013,0.00002570928,0.0001056387,0.9976458,0.0001274408,0.00007394327,0.001831143],"study_design_scores_gemma":[0.00001277831,0.0001311887,0.0005308018,0.000006048673,0.00002016198,0.0001079189,0.00001770648,0.001490616,0.9915106,0.00005685718,0.006104818,0.00001041238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5656394,0.002913887,0.4161636,0.000472366,0.000315342,0.001638152,0.002543165,0.001948324,0.008365689],"genre_scores_gemma":[0.6423156,0.003603132,0.3311035,0.000285851,0.00006205488,0.00146939,0.006760472,0.0004501549,0.01394987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008416004,"threshold_uncertainty_score":0.003249228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01743989689279509,"score_gpt":0.3157452692508312,"score_spread":0.2983053723580361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}