{"id":"W2899999076","doi":"10.1016/b978-0-12-813288-3.00022-7","title":"Epigenetics and Epigenomics","year":2018,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Center for Research Resources; Specialized Research Fund for the Doctoral Program of Higher Education of China; Canadian Institutes of Health Research; National Institutes of Health; Ministry of Education, Culture, Sports, Science and Technology; National Natural Science Foundation of China; Heart and Stroke Foundation of Canada","keywords":"Epigenetics; Biology; Multicellular organism; DNA methylation; Epigenomics; Genetics; Epigenetics of physical exercise; Histone; Inheritance (genetic algorithm); Epigenetic regulation of neurogenesis; Organism; DNA; Gene; Evolutionary biology; Gene expression; Histone methyltransferase","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003227204,0.000806593,0.0005226727,0.0009989928,0.0003951118,0.002093147,0.0005944425,0.001234526,0.07782776],"category_scores_gemma":[0.0003336568,0.0002978017,0.0002453702,0.001149176,0.0008232202,0.00221792,0.001299947,0.00170848,0.03944019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006722525,"about_ca_system_score_gemma":0.0006202349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000876808,"about_ca_topic_score_gemma":0.00157929,"domain_scores_codex":[0.999837,0.00001696816,0.000007561613,0.00004343522,0.00007917601,0.00001589209],"domain_scores_gemma":[0.9999259,0.00002453795,0.000006195954,0.00001481396,0.00001459596,0.00001402489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003615621,0.00004178189,0.0001760395,0.0004183446,0.00001092202,0.0001790983,0.0001271394,0.0004287402,0.01495345,0.08612259,0.08671104,0.8107947],"study_design_scores_gemma":[0.000003154957,0.00001045241,0.0003270471,0.000106449,0.00000428953,0.0002450774,0.0000372595,0.0001537339,0.002346953,0.02306094,0.9736986,0.000005997046],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.003453378,0.1688135,0.0344978,0.006486261,0.004132433,0.00004761035,0.0008998401,0.001011695,0.7806575],"genre_scores_gemma":[0.01027165,0.05742275,0.007539265,0.000998168,0.001091601,0.00005804441,0.0005383822,0.0001777894,0.9219024],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.07782776,"threshold_uncertainty_score":0.2603598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0120459123228849,"score_gpt":0.2367827460425228,"score_spread":0.2247368337196379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}