{"id":"W2900038271","doi":"","title":"Inhibition of skeletal metastasis in prostate cancer growth by S-adenosylmethionine (SAM) and methyl binding domain protein 2 (MBD2) knockdown.","year":2007,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cancer research; Gene knockdown; Metastasis; LNCaP; Prostate cancer; Biology; Tumor progression; Gene silencing; Cancer; Cancer cell; Intravasation; Cell culture; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001573311,0.0004492752,0.0004025042,0.0003011034,0.0001928302,0.0002384449,0.0002735977,0.0002549286,0.001660049],"category_scores_gemma":[0.00006155726,0.0001863558,0.0004059294,0.0003144245,0.0002359717,0.000140953,0.0001942059,0.0006838184,0.000363901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002457364,"about_ca_system_score_gemma":0.0003808144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001984432,"about_ca_topic_score_gemma":0.003812788,"domain_scores_codex":[0.999821,0.00002565334,0.00001590102,0.0000341529,0.00004955196,0.00005376076],"domain_scores_gemma":[0.9999465,0.000007571793,0.00001125909,0.000006444355,0.000006687267,0.00002163158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002609118,0.00008312953,0.000116105,0.00009233764,0.0000110893,0.00004054532,0.00001738324,0.00007640859,0.9971379,0.00008111668,0.0001401441,0.001942976],"study_design_scores_gemma":[0.00006819647,0.001486706,0.004441107,0.000006502883,0.00003779426,0.0001791888,0.00003514165,0.001268386,0.9877852,0.00003093524,0.004654278,0.000006457737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875975,0.00488282,0.002561416,0.0002159449,0.0001221218,0.0001096666,0.001323532,0.0002559462,0.002931052],"genre_scores_gemma":[0.9864854,0.002446385,0.002984961,0.0000741264,0.00001482531,0.0001757943,0.001662599,0.00002958883,0.00612631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001984432,"threshold_uncertainty_score":0.005553424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02839918041597233,"score_gpt":0.3688811410202639,"score_spread":0.3404819606042915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}