{"id":"W2900151022","doi":"10.1101/465435","title":"Transcriptional regulatory networks that promote and restrict identities and functions of intestinal innate lymphoid cells","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"York University; Flatiron Health; Cincinnati Children's Hospital Medical Center; NYU Langone Medical Center; Damon Runyon Cancer Research Foundation; Simons Foundation","keywords":"Biology; Innate lymphoid cell; Transcription factor; Chromatin; Gene regulatory network; Epigenetics; Effector; Regulation of gene expression; Transcriptional regulation; Innate immune system; Function (biology); Computational biology; Immune system; Systems biology; Gene; Genetics; Cell biology; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001492124,0.0002098439,0.0001605177,0.0002632263,0.0001686143,0.0003832713,0.0001398502,0.0001406137,0.00161405],"category_scores_gemma":[0.000177417,0.0001126211,0.0001647302,0.0002012366,0.0002543435,0.0002232458,0.0002174355,0.0002493846,0.0003359263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003888173,"about_ca_system_score_gemma":0.0003043947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006589668,"about_ca_topic_score_gemma":0.0008421302,"domain_scores_codex":[0.9998561,0.00001748463,0.000005959931,0.0000572995,0.00002734838,0.00003581897],"domain_scores_gemma":[0.9998389,0.00003405474,0.00004712474,0.00001843268,0.00002581553,0.00003557101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009808633,0.00001095788,0.003215696,0.00003828527,0.00000492361,0.00003044656,0.00003397038,0.0004588114,0.9914919,0.0008669707,0.00009901895,0.003650954],"study_design_scores_gemma":[0.00005713026,0.00023333,0.09665478,0.00006791235,0.00008095136,0.0003867225,0.000266644,0.02458299,0.8604106,0.003264676,0.01397483,0.00001934917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9671189,0.001741575,0.02571701,0.0001360452,0.00002607693,0.00003581648,0.001008032,0.0003051603,0.003911443],"genre_scores_gemma":[0.9913641,0.0004492571,0.006054489,0.00005416918,0.00001578018,0.0000399508,0.000779179,0.00003001145,0.001213022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00161405,"threshold_uncertainty_score":0.005399585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01442414965330119,"score_gpt":0.1919009959462337,"score_spread":0.1774768462929326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}