{"id":"W2900156386","doi":"10.1016/j.celrep.2018.10.043","title":"Characterization of a Mouse Model of Börjeson-Forssman-Lehmann Syndrome","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Human Genome Research Institute; National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute of Environmental Health Sciences; Center for Cellular Imaging, Washington University; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Washington University School of Medicine in St. Louis; National Cancer Institute; Washington University in St. Louis; Intellectual and Developmental Disabilities Research Center, Washington University School of Medicine in St. Louis; National Institutes of Health; Genome Technology Access Center","keywords":"Pathogenesis; Biology; Knockout mouse; Neuroscience; Transcriptome; Haploinsufficiency; Phenotype; Gene; Genetics; Gene expression; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004103636,0.001068158,0.0004457911,0.001780021,0.0005131068,0.0005261901,0.0006447318,0.001418519,0.004854175],"category_scores_gemma":[0.0003526561,0.0003834105,0.000682205,0.0003871222,0.0006489791,0.0005407747,0.0004693862,0.001764718,0.001321327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004686847,"about_ca_system_score_gemma":0.0004589249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008537414,"about_ca_topic_score_gemma":0.001458491,"domain_scores_codex":[0.9995419,0.0000487916,0.0000686415,0.0001316325,0.0001330992,0.00007597487],"domain_scores_gemma":[0.9995853,0.00006263948,0.0001222873,0.00003762936,0.0000385904,0.000153503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002278623,0.0002006436,0.0006594936,0.00008229331,0.00003151773,0.001139116,0.00007847227,0.0001782649,0.9920073,0.001481801,0.0004348466,0.003478247],"study_design_scores_gemma":[0.000338433,0.001256793,0.01448816,0.0001304617,0.000182652,0.01247998,0.0002207166,0.003682145,0.9364976,0.001199883,0.02946142,0.0000618101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9521319,0.002219137,0.0291518,0.001195944,0.0002914104,0.0005377493,0.007267585,0.001102258,0.006102221],"genre_scores_gemma":[0.9386569,0.003025062,0.02629868,0.0003198015,0.00007333512,0.0009820837,0.007979073,0.0003593685,0.02230574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004854175,"threshold_uncertainty_score":0.01623881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009544090396347472,"score_gpt":0.2076133732636357,"score_spread":0.1980692828672883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}