{"id":"W2900159171","doi":"10.1111/all.13658","title":"Preventive sublingual immunotherapy with House Dust Mite extract modulates epitope diversity in pre‐school children","year":2018,"lang":"en","type":"article","venue":"Allergy","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Hospital for Sick Children; Austrian Science Fund; HSBC Bank USA","keywords":"Sublingual immunotherapy; House dust mite; Medicine; Immunology; Epitope; Immunotherapy; Diversity (politics); Pyroglyphidae; Dust mites; Allergy; Allergen; Immune system; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001714698,0.0002029757,0.0003150813,0.0001764976,0.0001741577,0.000198991,0.0001119649,0.0002042434,0.0009962963],"category_scores_gemma":[0.0002507962,0.000107892,0.0001425948,0.0001017236,0.0002015896,0.0001434168,0.0001204195,0.0003708321,0.0001511555],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001433775,"about_ca_system_score_gemma":0.0001624837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005010467,"about_ca_topic_score_gemma":0.0006368719,"domain_scores_codex":[0.9999169,0.00001546077,0.000003529693,0.00001990806,0.00001563171,0.00002853513],"domain_scores_gemma":[0.9998635,0.0000311619,0.00003928485,0.000007094593,0.00001284812,0.00004601158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.009279887,0.004577318,0.2403817,0.0004824759,0.000113014,0.0008078595,0.0007444082,0.000264907,0.694897,0.00006482528,0.0004950342,0.04789171],"study_design_scores_gemma":[0.0001498776,0.01439659,0.9449786,0.00001556621,0.00006618501,0.0006869091,0.0002819958,0.000183439,0.03832783,0.00002903883,0.0008780344,0.000006006187],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996417,0.0001962449,0.00002979423,0.000008662994,0.000002252095,0.000006302288,0.00002115818,0.000004062185,0.00008979951],"genre_scores_gemma":[0.999411,0.000217686,0.0001194768,0.00002102757,0.000004485259,0.00001240178,0.00005899786,0.000001611062,0.0001532929],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009962963,"threshold_uncertainty_score":0.003332913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01183183539193976,"score_gpt":0.2441343989080255,"score_spread":0.2323025635160857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}