{"id":"W2900183696","doi":"10.1182/blood-2018-99-119086","title":"Efficacy and Safety of a Single Dose of Donor Lymphocytes Depleted of Alloreactive T-Cells (ATIR101) Following T-Cell-Depleted Haploidentical HSCT: A Pooled Analysis of Two Phase II Studies","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Hospital; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Medicine; Hematopoietic stem cell transplantation; Graft-versus-host disease; Stem cell; Internal medicine; Immune system; Transplantation; Immunology; T cell; Leukemia; Gastroenterology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006616211,0.001473669,0.003798035,0.0009235131,0.0002577077,0.001332807,0.0004662295,0.0008818758,0.001843451],"category_scores_gemma":[0.004651735,0.0005425975,0.005736673,0.0007811002,0.0004720755,0.0006884722,0.0004510186,0.001130177,0.000287435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005971421,"about_ca_system_score_gemma":0.0008267424,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002837586,"about_ca_topic_score_gemma":0.0006039896,"domain_scores_codex":[0.9967146,0.001839814,0.0004407207,0.0005073008,0.000339034,0.0001586448],"domain_scores_gemma":[0.9967532,0.001156907,0.001076954,0.0004043415,0.0003299554,0.000278576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.6991777,0.004820736,0.0238772,0.00486319,0.116583,0.0001913102,0.0001570532,0.002736749,0.03385412,0.000132091,0.001596173,0.1120106],"study_design_scores_gemma":[0.2121466,0.467856,0.113493,0.0006197605,0.1773307,0.0008102403,0.0002162097,0.00294399,0.01810536,0.0004339742,0.005873788,0.00017036],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9445091,0.04555956,0.00363409,0.0002188307,0.0001980472,0.002056601,0.00195013,0.0001215615,0.001752],"genre_scores_gemma":[0.9924135,0.003795121,0.001095476,0.0002418941,0.0001521643,0.0006707807,0.001178512,0.00001936656,0.0004333162],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006616211,"threshold_uncertainty_score":0.03499025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03347189124600687,"score_gpt":0.3430399669022948,"score_spread":0.309568075656288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}