{"id":"W2900214964","doi":"10.1002/cbic.201800548","title":"Global Folding of a Na<sup>+</sup>‐Specific DNAzyme Studied by FRET","year":2018,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"China Sponsorship Council; Ministerstvo Školství, Mládeže a Tělovýchovy; National Natural Science Foundation of China","keywords":"Deoxyribozyme; Förster resonance energy transfer; Chemistry; Folding (DSP implementation); Cleavage (geology); Circular dichroism; Biophysics; Crystallography; Fluorophore; G-quadruplex; Fluorescence; DNA; Biochemistry; Physics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003533434,0.0003175999,0.0005235014,0.00009186275,0.0001550586,0.0003161836,0.0003432205,0.0005186084,0.0005563266],"category_scores_gemma":[0.0003641048,0.0001455787,0.0002986789,0.0001330834,0.0002628295,0.0003631313,0.0001978649,0.0007055158,0.0004072977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000309466,"about_ca_system_score_gemma":0.0001065468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002626296,"about_ca_topic_score_gemma":0.0002120901,"domain_scores_codex":[0.999832,0.00002624616,0.00001113148,0.00006245354,0.00004086634,0.00002721257],"domain_scores_gemma":[0.9997924,0.00005351267,0.0000422033,0.00002650975,0.00005289554,0.00003253157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004007727,0.000008633931,0.0002115995,0.00001228003,0.000004000245,0.00002452441,0.00001999819,0.0001822827,0.9984642,0.00005474952,0.00001069823,0.0009668852],"study_design_scores_gemma":[0.000002669635,0.00006396727,0.0006184179,0.000001622358,0.000003064318,0.00006562594,0.00001452245,0.002039874,0.9968624,0.00002622491,0.0002986404,0.000003049278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849685,0.0003349861,0.01402171,0.00005741134,0.00001104777,0.00001342845,0.00007665719,0.00006255092,0.0004536823],"genre_scores_gemma":[0.9869982,0.0001706976,0.01138284,0.00003702482,0.000002906135,0.00001999697,0.0001970929,0.00003340728,0.001157928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005563266,"threshold_uncertainty_score":0.002245367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00994397549860619,"score_gpt":0.2695416924527796,"score_spread":0.2595977169541734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}