{"id":"W2900256197","doi":"10.1093/neuonc/noy148.060","title":"ACTR-27. PHASE 2 STUDY OF DIANHYDROGALACTITOL (VAL-083) IN PATIENTS WITH MGMT-UNMETHYLATED, BEVACIZUMAB-NAÏVE RECURRENT GLIOBLASTOMA","year":2018,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Delmar (Canada)","funders":"","keywords":"Temozolomide; Bevacizumab; Medicine; Oncology; Internal medicine; Phases of clinical research; Radiation therapy; Clinical trial; Cancer research; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009401208,0.001639317,0.001555409,0.000513659,0.0003200358,0.0007810988,0.0008108072,0.001044222,0.002710419],"category_scores_gemma":[0.0004513947,0.0005583777,0.001098795,0.0003521373,0.0008034303,0.0005760888,0.0002885798,0.002835691,0.001049058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008768489,"about_ca_system_score_gemma":0.001681549,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002346095,"about_ca_topic_score_gemma":0.005821712,"domain_scores_codex":[0.9997024,0.0001169241,0.00001217191,0.00005233878,0.00002845461,0.00008761995],"domain_scores_gemma":[0.9996848,0.00002535701,0.00003461202,0.00003067426,0.00002852116,0.0001961778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5354529,0.137007,0.005971668,0.0008661957,0.001593734,0.0007852469,0.0005838633,0.006009989,0.1692134,0.0008408545,0.01212767,0.1295474],"study_design_scores_gemma":[0.3935298,0.5766379,0.01159521,0.00002909378,0.0004112295,0.0004641477,0.00008035493,0.002152308,0.009545893,0.0003633094,0.005145043,0.00004583685],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990294,0.001244545,0.0006608305,0.0005379271,0.0001522101,0.002973886,0.001492494,0.0002297851,0.002414457],"genre_scores_gemma":[0.9836321,0.001521714,0.001930485,0.001212245,0.0001372203,0.003221576,0.00409865,0.00008018131,0.004165844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002710419,"threshold_uncertainty_score":0.009067297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01530027534252001,"score_gpt":0.3178220603997369,"score_spread":0.3025217850572169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}