{"id":"W2900256197","doi":"10.1093/neuonc/noy148.060","title":"ACTR-27. PHASE 2 STUDY OF DIANHYDROGALACTITOL (VAL-083) IN PATIENTS WITH MGMT-UNMETHYLATED, BEVACIZUMAB-NAÏVE RECURRENT GLIOBLASTOMA","year":2018,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Delmar (Canada)","funders":"","keywords":"Temozolomide; Bevacizumab; Medicine; Oncology; Internal medicine; Phases of clinical research; Radiation therapy; Clinical trial; Cancer research; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001596674,0.0003322581,0.0008316757,0.0004997323,0.00006920886,0.00001076741,0.0001535211,0.00017928,0.0001995591],"category_scores_gemma":[0.0001881109,0.0002303271,0.00008825377,0.0006650909,0.0001763699,0.0001068966,0.0001012652,0.0003487267,0.0001063703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003827461,"about_ca_system_score_gemma":0.000194394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001073307,"about_ca_topic_score_gemma":0.000845349,"domain_scores_codex":[0.9975412,0.0002915132,0.0005969501,0.0006188201,0.0004680642,0.0004834302],"domain_scores_gemma":[0.9982406,0.0003137421,0.0003426186,0.0005776202,0.0002765486,0.000248804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.02144015,0.08293489,0.7453447,0.00006148646,0.0005091752,0.001619186,0.004225974,0.000008507459,0.01289825,0.00001316533,0.002155146,0.1287894],"study_design_scores_gemma":[0.1507355,0.4033632,0.3298289,0.0001933187,0.001044969,0.00008911058,0.001058997,0.0001358863,0.08096338,0.00001986306,0.03203008,0.0005368608],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956833,0.00003891425,0.000001581609,0.0005234314,0.0007290265,0.002030186,0.00002092958,0.00004966976,0.0009230152],"genre_scores_gemma":[0.9993296,0.00002727211,0.00006375868,0.0002162625,0.0001336131,0.0001518195,0.00002228341,0.00004785703,0.000007556672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4155158,"threshold_uncertainty_score":0.9392466,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01530027534252001,"score_gpt":0.3178220603997369,"score_spread":0.3025217850572169,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}