{"id":"W2900316093","doi":"10.1039/c8qo00834e","title":"Trifluoromethylation of α-diazoesters and α-diazoketones with fluoroform-derived CuCF<sub>3</sub>: synergistic effects of co-solvent and pyridine as a promoter","year":2018,"lang":"en","type":"article","venue":"Organic Chemistry Frontiers","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Government of Northwest Territories","funders":"Chinese University of Hong Kong; Research Grants Council, University Grants Committee","keywords":"Chemistry; Trifluoromethylation; Pyridine; Solvent; Combinatorial chemistry; Medicinal chemistry; Organic chemistry; Trifluoromethyl","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001467395,0.0003866951,0.0002000009,0.00008490248,0.0001126931,0.00009677355,0.0002476675,0.0002890283,0.001077312],"category_scores_gemma":[0.0002685573,0.0001024686,0.0001406827,0.0001280045,0.0001974503,0.0003004124,0.0001757484,0.0003235602,0.0003463345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002211997,"about_ca_system_score_gemma":0.0002416822,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001285089,"about_ca_topic_score_gemma":0.002661963,"domain_scores_codex":[0.9998926,0.00001480546,0.000006720451,0.00002389828,0.00002210392,0.00003996048],"domain_scores_gemma":[0.9999349,0.00001450559,0.00001921222,0.000006180795,0.00001176524,0.00001337876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009689906,0.0000074465,0.00004765645,0.00007244957,0.000004954255,0.00004717127,0.00002461925,0.00006084874,0.9975156,0.0001155734,0.00005890428,0.001947949],"study_design_scores_gemma":[0.000004146119,0.00005842788,0.000181366,0.000003331377,0.000004328519,0.00008573652,0.000008808932,0.0001084358,0.998431,0.00001603358,0.00109453,0.000003852299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793505,0.003744938,0.0102501,0.0001242976,0.00008030955,0.00007402429,0.0003217057,0.0001602948,0.005893761],"genre_scores_gemma":[0.9924256,0.001475441,0.003920073,0.00003973081,0.00001035552,0.00001996644,0.0001825992,0.00002649125,0.001899752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001285089,"threshold_uncertainty_score":0.003603995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01402343999052093,"score_gpt":0.3016463250251388,"score_spread":0.2876228850346179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}