{"id":"W2900343625","doi":"10.1039/c8nj04041a","title":"Investigation of the cytotoxic potential of methyl imidazole-derived thiosemicarbazones and their copper(<scp>ii</scp>) complexes with dichloroacetate as a co-ligand","year":2018,"lang":"en","type":"article","venue":"New Journal of Chemistry","topic":"Metal complexes synthesis and properties","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Regional Development Fund; Agentúra Ministerstva Školstva, Vedy, Výskumu a Športu SR; Nemzeti Kutatási Fejlesztési és Innovációs Hivatal; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; Österreichische Austauschdienst; Agentúra na Podporu Výskumu a Vývoja; Emberi Eroforrások Minisztériuma; Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja; Agence Universitaire de la Francophonie; Austrian Science Fund","keywords":"Chemistry; Imidazole; Copper; Ligand (biochemistry); Cytotoxic T cell; Stereochemistry; Cytotoxicity; Medicinal chemistry; Organic chemistry; Receptor; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001026316,0.0001732016,0.0001425085,0.0001343907,0.0001202416,0.0000994018,0.0001574636,0.0001473,0.0008109161],"category_scores_gemma":[0.0001758388,0.00006616575,0.00008503423,0.0001934375,0.0001310303,0.0001043277,0.000102569,0.0001609571,0.0001251272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001376896,"about_ca_system_score_gemma":0.0001556415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007226298,"about_ca_topic_score_gemma":0.0009424333,"domain_scores_codex":[0.9999222,0.00002336164,0.000006297831,0.000009351277,0.00002504534,0.00001380717],"domain_scores_gemma":[0.9999115,0.00002030957,0.00002106954,0.000007348221,0.00002690963,0.00001280501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004622873,0.00003092835,0.0003566694,0.0001235558,0.00001434267,0.00008358137,0.00003309504,0.0002305314,0.9950708,0.0001146212,0.00008161859,0.003398021],"study_design_scores_gemma":[0.0000116589,0.0006305187,0.001642801,0.000003929024,0.0000202608,0.0001667332,0.00002418067,0.0003531927,0.9955309,0.00001652965,0.001595984,0.00000325625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941413,0.002811607,0.0007088505,0.00005348126,0.00001584275,0.00002049535,0.0001188295,0.00002744162,0.002102148],"genre_scores_gemma":[0.9968293,0.001036988,0.0006102791,0.00001334385,0.00000557141,0.00001269305,0.0001510037,0.000003796909,0.001336961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008109161,"threshold_uncertainty_score":0.002712786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02490530445473347,"score_gpt":0.2396596110508249,"score_spread":0.2147543065960915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}