{"id":"W2900357627","doi":"10.1002/ajh.25342","title":"Treatment‐free remission with first‐ and second‐generation tyrosine kinase inhibitors","year":2018,"lang":"en","type":"review","venue":"American Journal of Hematology","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Bristol-Myers Squibb","keywords":"Nilotinib; Dasatinib; Discontinuation; Medicine; Imatinib; Bosutinib; Clinical trial; Tyrosine-kinase inhibitor; Tyrosine kinase; Myeloid leukemia; Oncology; Intensive care medicine; Imatinib mesylate; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001218654,0.0004977272,0.003087793,0.0003635914,0.00008773272,0.00001630167,0.0001365535,0.0001880618,0.0001499425],"category_scores_gemma":[0.0001446916,0.0002850138,0.0003050247,0.000291358,0.0005015931,0.00007415404,0.0000507028,0.0003059333,0.00001548934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009696087,"about_ca_system_score_gemma":0.001560241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003684507,"about_ca_topic_score_gemma":0.00008943804,"domain_scores_codex":[0.9980004,0.0001592285,0.0009351337,0.0003674407,0.0002371507,0.0003006331],"domain_scores_gemma":[0.9969528,0.0002367794,0.001782365,0.0005281303,0.0001710867,0.0003288338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003577111,0.0003826644,0.0006053905,0.004629202,0.001810539,0.003225433,0.0002072492,1.526617e-7,0.00001300594,0.00004015044,0.01369105,0.9750375],"study_design_scores_gemma":[0.003543172,0.01048202,0.00001548942,0.01096494,0.003072274,0.08464441,0.00005240974,0.000003859804,0.000150088,0.000006246868,0.8868157,0.000249429],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01116729,0.9876006,0.00002054638,0.00035736,0.0002042768,0.0004442304,0.00001643359,0.00001567063,0.0001735693],"genre_scores_gemma":[0.001480428,0.9940636,0.003178994,0.00005658214,0.0006713634,0.00002081044,0.00005382023,0.00007544324,0.0003990214],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.974788,"threshold_uncertainty_score":0.9999602,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02730329211227252,"score_gpt":0.3110332930561482,"score_spread":0.2837300009438757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}