{"id":"W2900403864","doi":"10.1038/s41598-018-34339-1","title":"Intrinsic disorder in the regulatory N-terminal domain of diacylglycerol acyltransferase 1 from Brassica napus","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Biological and Environmental Research; National Institute of General Medical Sciences; Basic Energy Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Office of Science; National Institutes of Health; Canada Research Chairs; Deutsche Forschungsgemeinschaft; SLAC National Accelerator Laboratory; University of Alberta; York University; Alberta Innovates - Health Solutions; Alberta Canola Producers Commission; Technische Universität Kaiserslautern; Alberta Innovates; U.S. Department of Energy; Heart and Stroke Foundation of Canada","keywords":"Allosteric regulation; Diacylglycerol kinase; Biophysics; Biochemistry; Chemistry; Intrinsically disordered proteins; Protein domain; Biology; Cell biology; Computational biology; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008665428,0.0002058056,0.0001717993,0.0001062948,0.0001574241,0.0001857052,0.0001499904,0.0001821631,0.0003328121],"category_scores_gemma":[0.0001795617,0.00007872992,0.0001388327,0.0001113953,0.0002560038,0.0001991719,0.0001308282,0.0003269201,0.0001631256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002718211,"about_ca_system_score_gemma":0.0001349987,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005211567,"about_ca_topic_score_gemma":0.0007745923,"domain_scores_codex":[0.9999294,0.00001342108,0.000007165878,0.00002217379,0.00001861373,0.000009218497],"domain_scores_gemma":[0.9998599,0.00003401884,0.00005089165,0.00001540138,0.0000142608,0.00002540338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004439378,0.00001162136,0.0007172155,0.00002536291,0.000005479112,0.00007635183,0.0000320969,0.0001274603,0.9983184,0.00007742036,0.00002128098,0.0005429558],"study_design_scores_gemma":[0.00001300831,0.0001650499,0.02954286,0.0000110964,0.00003150254,0.001548002,0.0001118972,0.004243108,0.9615733,0.0003294627,0.002410203,0.0000206207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970793,0.0004036969,0.002119114,0.00005093514,0.000005765983,0.000004844769,0.00007474132,0.0000230497,0.0002385745],"genre_scores_gemma":[0.9976504,0.0001640459,0.001260252,0.00005204181,0.000004622574,0.000008660757,0.0003891662,0.000009575529,0.0004612404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005211567,"threshold_uncertainty_score":0.001972258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005855939941454079,"score_gpt":0.2238831386729907,"score_spread":0.2180271987315366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}