{"id":"W2900437800","doi":"10.1016/j.molmet.2018.10.012","title":"The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones","year":2018,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Novo Nordisk; Novo Nordisk Foundation Center for Basic Metabolic Research; Danish Diabetes Academy; Novo Nordisk Fonden; Medical Research Council Canada; Copenhagen Graduate School for Nanoscience and Nanotechnology; Wellcome Trust","keywords":"Hormone; Metabolism; Chemistry; Endocrinology; Internal medicine; Biochemistry; Biology; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001019326,0.0002898711,0.0003353482,0.0001459789,0.0001040893,0.0003139407,0.0001550195,0.0002367544,0.0008819464],"category_scores_gemma":[0.0001122122,0.0001595179,0.0002488353,0.0001351526,0.0001615956,0.0002944949,0.0003761619,0.0003402371,0.0003992542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000170153,"about_ca_system_score_gemma":0.00009994347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001963286,"about_ca_topic_score_gemma":0.0002246482,"domain_scores_codex":[0.9998417,0.00002868322,0.00001012006,0.00004235057,0.00002468794,0.00005249424],"domain_scores_gemma":[0.9999431,0.000003794318,0.00001797737,0.000007702705,0.000009821591,0.00001753381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002666685,0.000008625068,0.0004437823,0.00001599729,0.000007001478,0.0000646814,0.000008871706,0.00005327219,0.9975706,0.00009639707,0.00006032617,0.001403741],"study_design_scores_gemma":[0.0001198765,0.001103916,0.06554917,0.00001305991,0.00009544624,0.001364882,0.0001832567,0.005070584,0.9147099,0.0004795484,0.01127408,0.00003635314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927977,0.0009106682,0.004340155,0.0001453132,0.00003538811,0.00001574193,0.0002872081,0.0000976081,0.001370234],"genre_scores_gemma":[0.9950374,0.0006507213,0.001849597,0.00009981127,0.00001980007,0.0000223154,0.000402321,0.00002555883,0.001892441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008819464,"threshold_uncertainty_score":0.00295037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0081726132542687,"score_gpt":0.2383926128041264,"score_spread":0.2302199995498576,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}