{"id":"W2900582712","doi":"10.3389/fped.2018.00350","title":"Celiac Disease: A Review of Current Concepts in Pathogenesis, Prevention, and Novel Therapies","year":2018,"lang":"en","type":"review","venue":"Frontiers in Pediatrics","topic":"Celiac Disease Research and Management","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"","keywords":"Disease; Medicine; Human leukocyte antigen; Immunology; Genetic predisposition; Malabsorption; Gluten; Pathogenesis; Immune system; Mechanism (biology); Immune dysregulation; Population; Pathology; Environmental health; Antigen; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008574954,0.0003541375,0.001763661,0.0007540052,0.00002142359,0.00001306208,0.0002022549,0.0001170319,0.00003858357],"category_scores_gemma":[0.0005008621,0.0002912236,0.0004079362,0.001020044,0.000143714,0.00006086432,0.0001886949,0.0002965643,0.000005305729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002049394,"about_ca_system_score_gemma":0.001083853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003963497,"about_ca_topic_score_gemma":0.000002246964,"domain_scores_codex":[0.9973605,0.000202677,0.0009477587,0.0005237796,0.0005839915,0.0003813513],"domain_scores_gemma":[0.9986078,0.0000611929,0.0003727843,0.0004955083,0.0001417485,0.0003210029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002505583,0.0003318634,0.00285134,0.3673446,0.00004968855,0.00002188893,0.00001369643,1.662885e-8,1.02686e-8,0.00003424877,0.04620764,0.58312],"study_design_scores_gemma":[0.0006759356,0.00007248038,0.0007940613,0.1017316,0.001439356,0.000001794509,0.00001912608,0.000003017989,1.636137e-8,0.00009102505,0.8949574,0.0002142234],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00000515181,0.9950444,0.0009753365,0.00005942253,0.0006148065,0.002984909,0.0002335705,0.00001362807,0.00006882624],"genre_scores_gemma":[0.000001514968,0.9976464,0.0009056148,0.00004684307,0.0003462974,0.0003670655,0.0004089719,0.00004204227,0.0002352552],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8487498,"threshold_uncertainty_score":0.999954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04689050237141807,"score_gpt":0.3965717580213105,"score_spread":0.3496812556498924,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}