{"id":"W2900756811","doi":"10.1080/20013078.2018.1535750","title":"Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines","year":2018,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11150,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; Okanagan University College; University of British Columbia, Okanagan Campus; Princess Margaret Cancer Centre; Canada's Michael Smith Genome Sciences Centre; Toronto General Hospital; University of Toronto; Ottawa Hospital; University Health Network; McGill University Health Centre; Simon Fraser University; McGill University; University of Ottawa; University of British Columbia; Centre hospitalier de l'Université Laval; Atlantic Cancer Research Institute; Mount Allison University","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institute on Drug Abuse; National Institute of Mental Health; National Heart, Lung, and Blood Institute; National Institute on Aging; Medical Research Council; Institut National Du Cancer; Institut National de la Santé et de la Recherche Médicale; National Institute of Diabetes and Digestive and Kidney Diseases; Biotechnology and Biological Sciences Research Council; National Center for Advancing Translational Sciences; Fondation ARC pour la Recherche sur le Cancer; Agence Nationale de la Recherche; National Institutes of Health; Cancer Research UK; Sidaction","keywords":"Extracellular vesicles; Vesicle; Microvesicles; Extracellular; Position (finance); Statement (logic); Chemistry; Biology; Cell biology; Political science; Biochemistry; Law; Business","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.05277022,0.00160073,0.002537068,0.007374138,0.001944165,0.00779679,0.006772422,0.01486778,0.01693126],"category_scores_gemma":[0.09178736,0.001417883,0.003743702,0.002949595,0.003254622,0.005367385,0.00940558,0.009273566,0.01970648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003973011,"about_ca_system_score_gemma":0.0189954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003507868,"about_ca_topic_score_gemma":0.004586885,"domain_scores_codex":[0.9594204,0.01496309,0.01222664,0.001288654,0.01035122,0.001749884],"domain_scores_gemma":[0.8970595,0.03968067,0.009942457,0.00550252,0.04339852,0.004416388],"domain_codex":null,"domain_gemma":"reporting","domain_candidate":"reporting","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003840313,0.0001318207,0.0007876287,0.008884974,0.00008293331,0.0006340201,0.0006509434,0.0003822876,0.003664003,0.02493903,0.7868552,0.1726031],"study_design_scores_gemma":[0.00004155119,0.00006538928,0.0006308922,0.006518646,0.00005976568,0.000333139,0.0001709697,0.0001288542,0.001194347,0.00646493,0.984345,0.00004647765],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.005216074,0.2144628,0.1399847,0.3650959,0.08505006,0.009874909,0.03428966,0.008282103,0.1377438],"genre_scores_gemma":[0.02131076,0.1756788,0.3122836,0.2678223,0.02376082,0.02443895,0.07471041,0.003708587,0.09628572],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.9472298,"threshold_uncertainty_score":0.2790789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02878956252801908,"score_gpt":0.3070259047046972,"score_spread":0.2782363421766781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}