{"id":"W2900785236","doi":"10.1139/cjpp-2018-0505","title":"Circular RNAs constitute an inherent gene regulatory axis in the mammalian eye and brain","year":2018,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health","keywords":"Biology; microRNA; Biogenesis; Circular RNA; Computational biology; Translation (biology); RNA-binding protein; RNA splicing; Gene; Regulation of gene expression; RNA; Gene expression; Genetics; Alternative splicing; Cell biology; Neuroscience; Messenger RNA","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003347975,0.0003185372,0.0003465338,0.0005726377,0.0004730576,0.001160276,0.0003324749,0.0006693514,0.001644216],"category_scores_gemma":[0.0004147069,0.000234384,0.0003325453,0.000258321,0.001179466,0.00107076,0.0007443378,0.0009953381,0.0009622213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005127005,"about_ca_system_score_gemma":0.000803276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006377979,"about_ca_topic_score_gemma":0.0009092565,"domain_scores_codex":[0.9995473,0.00005059548,0.00003297549,0.0001961476,0.0001223598,0.00005052239],"domain_scores_gemma":[0.9996934,0.00005591237,0.00009196378,0.00002343016,0.0000831951,0.00005211537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002382037,0.0000299061,0.002430542,0.0009720151,0.00005197587,0.0008414015,0.0005690162,0.0002482295,0.8125834,0.03807642,0.003005907,0.140953],"study_design_scores_gemma":[0.00004838269,0.001027376,0.0453879,0.0007039563,0.0002419795,0.008873287,0.001067633,0.001539508,0.3868484,0.04605975,0.5079955,0.000206379],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.2664412,0.5263439,0.1312585,0.006973226,0.002409739,0.0001499284,0.001658701,0.001902235,0.06286252],"genre_scores_gemma":[0.7799635,0.133264,0.05277887,0.003842226,0.001655695,0.0001978898,0.001557227,0.0005061825,0.02623432],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001644216,"threshold_uncertainty_score":0.005500495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0281483003726442,"score_gpt":0.3262239064750361,"score_spread":0.2980756061023919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}