{"id":"W2900828661","doi":"10.15698/mic2018.12.662","title":"Insights into the host-pathogen interaction: C. albicans manipulation of macrophage pyroptosis","year":2018,"lang":"en","type":"letter","venue":"Microbial Cell","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Pyroptosis; Candida albicans; Pathogen; Virulence; Macrophage; Fungal pathogen; Corpus albicans; Microbiology; Host (biology); Immune system; Biology; Human pathogen; Disease; Immunology; Medicine; Bacteria; Inflammation; Inflammasome; Genetics; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006833905,0.000290372,0.000455557,0.0001807627,0.0002371232,0.00003020331,0.0001432259,0.0004274798,0.0004490543],"category_scores_gemma":[0.00002326702,0.0001961314,0.0002682462,0.000226971,0.000221112,0.00005165533,0.0001149708,0.0009148174,0.0002502366],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001522274,"about_ca_system_score_gemma":0.00005831937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006705679,"about_ca_topic_score_gemma":0.0001340615,"domain_scores_codex":[0.998753,0.00008909366,0.0004184077,0.0003419311,0.0001898879,0.0002077043],"domain_scores_gemma":[0.9988517,0.00008512574,0.0002560946,0.0004755621,0.0002997069,0.00003178926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000398032,0.00005390974,0.0000708068,0.000268934,0.0001091285,0.0000408001,0.001181544,0.000001099038,0.3507626,0.000002035694,0.6473711,0.0000983189],"study_design_scores_gemma":[0.0003561826,0.0003126558,0.0006594987,0.000157088,0.0003437237,0.000028424,0.0001148811,0.00001235548,0.06637511,0.0000124842,0.9314428,0.000184825],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6256296,0.004246552,0.0002921549,0.3113031,0.00665286,0.002207558,0.0001483355,0.0001863408,0.04933353],"genre_scores_gemma":[0.7073566,0.000803647,0.000680024,0.2444502,0.0151448,0.00007495411,0.0009896986,0.000169514,0.03033055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2843875,"threshold_uncertainty_score":0.7998008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01763342143985641,"score_gpt":0.2504251538436428,"score_spread":0.2327917324037864,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}