{"id":"W2900871258","doi":"10.3389/fnins.2018.00838","title":"Phoenixin Expression Is Regulated by the Fatty Acids Palmitate, Docosahexaenoic Acid and Oleate, and the Endocrine Disrupting Chemical Bisphenol A in Immortalized Hypothalamic Neurons","year":2018,"lang":"en","type":"article","venue":"Frontiers in Neuroscience","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Internal medicine; Kisspeptin; Endocrinology; Docosahexaenoic acid; Hypothalamus; Gonadotropin-releasing hormone; Biology; Leptin; Hormone; Chemistry; Fatty acid; Polyunsaturated fatty acid; Biochemistry; Luteinizing hormone; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001464957,0.000201526,0.0002252385,0.0002135998,0.0002948157,0.0004095678,0.0001619473,0.0002359882,0.001047544],"category_scores_gemma":[0.00009272153,0.0001742156,0.0003450941,0.0002365712,0.000341103,0.0002920211,0.0003066942,0.0006161612,0.0002958335],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003499725,"about_ca_system_score_gemma":0.0002881651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001129894,"about_ca_topic_score_gemma":0.001547686,"domain_scores_codex":[0.9998078,0.00001317869,0.00002256881,0.00005794195,0.00004796351,0.00005074656],"domain_scores_gemma":[0.999917,0.00001439275,0.00002192547,0.0000112177,0.00001077602,0.00002466895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001527116,0.00001703611,0.0003453361,0.00001963687,0.00000561465,0.00005379683,0.00002578509,0.00002823712,0.998435,0.00008596102,0.0000284619,0.0008025457],"study_design_scores_gemma":[0.00002052343,0.0001224938,0.01665282,0.000008659715,0.00002088085,0.0001942759,0.000134965,0.0005283792,0.9792855,0.0001054085,0.002918886,0.000007160038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908537,0.001645604,0.004247212,0.0001643727,0.00007729443,0.00002707933,0.001296632,0.0000484305,0.001639728],"genre_scores_gemma":[0.9837155,0.002519446,0.003998517,0.0001034905,0.00002252042,0.0001059495,0.002387056,0.00003668542,0.007110932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001129894,"threshold_uncertainty_score":0.003504395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01058047863611674,"score_gpt":0.2495586294270807,"score_spread":0.238978150790964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}